Domínguez-Rodríguez Alberto, Baéz-Ferrer Néstor, Avanzas Pablo, Rodríguez Sergio, Abreu-González Pedro, Trujillo-Martin Elisa, Burillo-Putze Guillermo, Hernández-Vaquero Daniel
Departamento de Medicina Interna, Universidad de La Laguna, Servicio de Cardiología, Hospital Universitario de Canarias, 38320 Tenerife, Spain.
Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares (CIBERCV), 28029 Madrid, Spain.
J Clin Med. 2024 Apr 19;13(8):2392. doi: 10.3390/jcm13082392.
Recently, desert dust in Europe has been recognized as a cardiovascular health problem. In Spain, desert dust inflows in recent years have been associated with worsening air quality. The present study examines whether desert dust events are related to the incidence of acute coronary syndrome (ACS) in patients under 55 years of age. Data from 2416 consecutive patients admitted to a tertiary hospital due to ACS were prospectively analyzed. A case-crossover time-stratified design using Poisson conditional regression models was applied to estimate the impact of desert dust events involving particulate matter concentrations of an aerodynamic diameter <10 μm (PM) on the incidence of ACS in patients under 55 years of age. Desert dust intrusion on days 0 to 5 before ACS onset showed no significant association with the incidence of ACS in patients under 55 years of age. The incidence rate ratios of PM concentrations 1, 2, 3, 3, 4, and 5 days before ACS onset (for changes of 10 µg/m) were 1.02 (95% CI 0.97-1.1; = 0.41), 1.01 (95% CI 0.96-1.07; = 0.66), 0.99 (95% CI 0.94-1.05; = 0.78), 0.96 (95% CI 0.9-1.02; = 0.18), and 0.97 (95% CI 0.91-1.04; = 0.41). Our findings suggest that desert dust is unlikely to be related to the incidence of ACS in patients under 55 years of age.
最近,欧洲的沙漠尘土已被视为一个心血管健康问题。在西班牙,近年来沙漠尘土的流入与空气质量恶化有关。本研究调查了沙漠尘土事件是否与55岁以下患者的急性冠状动脉综合征(ACS)发病率相关。对一家三级医院因ACS连续收治的2416例患者的数据进行了前瞻性分析。采用泊松条件回归模型的病例交叉时间分层设计,以评估涉及空气动力学直径<10μm颗粒物(PM)的沙漠尘土事件对55岁以下患者ACS发病率的影响。ACS发病前0至5天的沙漠尘土侵入与55岁以下患者的ACS发病率无显著关联。ACS发病前1、2、3、4和5天PM浓度(变化10μg/m)的发病率比分别为1.02(95%CI 0.97-1.1;P = 0.41)、1.01(95%CI 0.96-1.07;P = 0.66)、0.99(95%CI 0.94-1.05;P = 0.78)、0.96(95%CI 0.9-1.02;P = 0.18)和0.97(95%CI 0.91-1.04;P = 0.41)。我们的研究结果表明,沙漠尘土不太可能与55岁以下患者的ACS发病率相关。