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沙尘事件对心血管疾病的影响:一项系统评价和荟萃分析。

Impact of Desert Dust Events on the Cardiovascular Disease: A Systematic Review and Meta-Analysis.

作者信息

Domínguez-Rodríguez Alberto, Báez-Ferrer Néstor, Abreu-González Pedro, Rodríguez Sergio, Díaz Rocío, Avanzas Pablo, Hernández-Vaquero Daniel

机构信息

Servicio de Cardiología, Hospital Universitario de Canarias, 38010 Tenerife, Spain.

Departamento de Enfermería, Universidad de La Laguna, 38200 Tenerife, Spain.

出版信息

J Clin Med. 2021 Feb 12;10(4):727. doi: 10.3390/jcm10040727.

Abstract

BACKGROUND

Whether or not inhalation of airborne desert dust has adverse health effects is unknown. The present study, based on a systematic review and meta-analysis, was carried out to assess the influence desert dust on cardiovascular mortality, acute coronary syndrome, and heart failure.

METHODS

A systematic search was made in PubMed and Embase databases for studies published before March 2020. Studies based on daily measurements of desert dust were identified. The meta-analysis evaluated the impact of desert dust on cardiovascular events the same day (lag 0) of the exposure and during several days after the exposure (lags 1 to 5). The combined impact of several days of exposure was also evaluated. The incidence rate ratio (IRR) with 95% confidence intervals (CI) was calculated using the inverse variance random effects method.

RESULTS

Of the 589 identified titles, a total of 15 studies were selected. The impact of desert dust on the incidence of cardiovascular mortality was statistically significant (IRR = 1.018 (95%CI 1.008-1.027); < 0.001) in lag 0 of the dust episode, in the following day (lag 1) (IRR = 1.005 (95%CI 1.001-1.009); = 0.022), and during both days combined (lag 0-1) (IRR = 1.015 (95%CI 1.003-1.028); = 0.014).

CONCLUSIONS

The inhalation to desert dust results in a 2% increase (for every 10 µg/m) in cardiovascular mortality risk.

摘要

背景

吸入空气中的沙漠尘土是否会对健康产生不良影响尚不清楚。本研究基于系统评价和荟萃分析,旨在评估沙漠尘土对心血管疾病死亡率、急性冠状动脉综合征和心力衰竭的影响。

方法

在PubMed和Embase数据库中进行系统检索,查找2020年3月之前发表的研究。确定基于每日沙漠尘土测量的研究。荟萃分析评估了沙漠尘土在暴露当天(滞后0天)以及暴露后几天(滞后1至5天)对心血管事件的影响。还评估了连续几天暴露的综合影响。采用逆方差随机效应方法计算95%置信区间(CI)的发病率比(IRR)。

结果

在589篇已识别的标题中,共选择了15项研究。沙漠尘土对心血管疾病死亡率发病率的影响在沙尘事件的滞后0天(IRR = 1.018(95%CI 1.008 - 1.027);P < 0.001)、次日(滞后1天)(IRR = 1.005(95%CI 1.001 - 1.009);P = 0.022)以及两天综合(滞后0 - 1天)(IRR = 1.015(95%CI 1.003 - 1.028);P = 0.014)时具有统计学意义。

结论

吸入沙漠尘土会使心血管疾病死亡风险增加2%(每10微克/立方米)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/046c/7918944/02c5f8f3dc29/jcm-10-00727-g001.jpg

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