in Supportive Periodontal Therapy-Are There Already Clinical Effects after 3 Months with One Lozenge a Day? A Double-Blind Randomized Placebo-Controlled Study.

AIM

The purpose of this study was to investigate whether a clinical effect of in supportive periodontal therapy can already be detected with a minimum dose of one tablet a day and a minimum observation and intake period of 3 months.

MATERIALS AND METHODS

28 patients with stage III and IV periodontitis undergoing periodontal follow-up were randomly divided into two groups receiving a lozenge containing or a placebo preparation daily for 90 days. After 0, 4, 8, and 12 weeks, the parameters bleeding on probing (BoP), plaque control record (PCR), periodontal probing depth (PPD), and clinical attachment level (CAL) were recorded in the test and control groups.

RESULTS

The results sed a different effect of on the respective patients. In certain patients, clinical parameters worsened or remained largely unchanged. However, in other patients, there were positive effects on the clinical parameters. In the overall analysis, BoP was the only clinical parameter that was statistically significantly reduced.

CONCLUSIONS

The oral administration of one lozenge per day for 3 months with in supportive periodontal therapy might have a positive influence on clinical parameters in supportive periodontal therapy, depending on the individual.