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Natural Infection with Highly Pathogenic Avian Influenza A/H5N1 Virus in Pet Ferrets.宠物雪貂感染高致病性禽流感 A/H5N1 病毒。
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2024年6月至9月禽流感概述

Avian influenza overview June-September 2024.

作者信息

Alexakis Leonidas, Buczkowski Hubert, Ducatez Mariette, Fusaro Alice, Gonzales Jose L, Kuiken Thijs, Ståhl Karl, Staubach Christoph, Svartström Olov, Terregino Calogero, Willgert Katriina, Delacourt Roxane, Kohnle Lisa

出版信息

EFSA J. 2024 Oct 21;22(10):e9057. doi: 10.2903/j.efsa.2024.9057. eCollection 2024 Oct.

DOI:10.2903/j.efsa.2024.9057
PMID:39434784
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11492803/
Abstract

Between 15 June and 20 September 2024, 75 highly pathogenic avian influenza (HPAI) A(H5) and A(H7) virus detections were reported in domestic (16) and wild (59) birds across 11 countries in Europe. Although the overall number of detections in Europe continued to be low compared to previous epidemiological years, an increase in cases along the Atlantic, North Sea and Baltic coasts was notable, particularly an increase in the detection of HPAI viruses in colony-breeding seabirds. Besides EA-2022-BB and other circulating genotypes, these detections also included EA-2023-DT, a new genotype that may transmit more efficiently among gulls. In Germany, HPAI A(H7N5) virus emerged in a poultry establishment near the border with the Netherlands. No new HPAI virus detections in mammals were reported in Europe during this period, but the number of reportedly affected dairy cattle establishments in the United States of America (USA) rose to >230 in 14 states, and HPAI virus was identified in three new mammal species. Between 21 June and 20 September 2024, 19 new human cases with avian influenza virus infection were reported from the USA (six A(H5N1) cases and five A(H5) cases), Cambodia (five A(H5N1) cases, including one fatal), China (one fatal A(H5N6) case and one A(H9N2) case), and Ghana (one A(H9N2) case). Most of the human cases (90%,  = 17/19) had reported exposure to poultry, live poultry markets, or dairy cattle prior to avian influenza virus detection or onset of illness. Human infections with avian influenza viruses remain rare and no evidence of human-to-human transmission has been documented in the reporting period. The risk of infection with currently circulating avian A(H5) influenza viruses of clade 2.3.4.4b in Europe remains low for the general public in the European Union/European Economic Area (EU/EEA). The risk of infection remains low-to-moderate for those occupationally or otherwise exposed to infected animals or contaminated environments.

摘要

2024年6月15日至9月20日期间,欧洲11个国家的家养(16例)和野生(59例)鸟类中报告了75起高致病性禽流感(HPAI)A(H5)和A(H7)病毒检测结果。尽管与之前的流行年份相比,欧洲的总体检测数量仍然较低,但大西洋、北海和波罗的海沿岸的病例数有所增加,值得注意的是,群居繁殖海鸟中HPAI病毒的检测数量有所增加。除了EA - 2022 - BB和其他流行基因型外,这些检测还包括EA - 2023 - DT,这是一种可能在海鸥中更高效传播的新基因型。在德国,HPAI A(H7N5)病毒在靠近荷兰边境的一家家禽养殖场出现。在此期间,欧洲没有报告哺乳动物中出现新的HPAI病毒检测结果,但据报道,美国14个州受影响的奶牛养殖场数量增至230多个,并且在三种新的哺乳动物物种中发现了HPAI病毒。2024年6月21日至9月20日期间,美国(6例A(H5N1)病例和5例A(H5)病例)、柬埔寨(5例A(H5N1)病例,包括1例死亡病例)、中国(1例A(H5N6)死亡病例和1例A(H9N2)病例)和加纳(1例A(H9N2)病例)报告了19例新的禽流感病毒感染人类病例。大多数人类病例(90%,即17/19)在禽流感病毒检测或发病前报告有接触家禽、活禽市场或奶牛的情况。在报告期内,人类感染禽流感病毒仍然罕见,并且没有记录到人际传播的证据。对于欧盟/欧洲经济区(EU/EEA)的普通公众来说,感染欧洲目前流行的2.3.4.4b分支A(H5)禽流感病毒的风险仍然较低。对于那些职业性或其他方式接触受感染动物或受污染环境的人来说,感染风险仍然为低到中度。