Di Giorgio Francesca Maria, Modica Stefania Pia, Saladino Marica, Muscarella Stefano, Ciminnisi Stefania, Almasio Piero Luigi, Petta Salvatore, Cappello Maria
Gastroenterology and Hepatology Section, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Piazza delle Cliniche, 2-90127 Palermo, Italy.
Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Piazza delle Cliniche, 2-90127 Palermo, Italy.
Nutrients. 2024 Apr 17;16(8):1193. doi: 10.3390/nu16081193.
Patients with inflammatory bowel disease (IBD) believe that diet plays a significant role in the pathogenesis of their disease and the exacerbation of their symptoms. They often adopt restrictive diets that can lead to malnutrition, anxiety, and stress. Recent studies have found a correlation between IBD and eating disorders, such as anorexia nervosa and ARFID (Avoidant Restrictive Food Intake Disorder). None of these studies report an association with orthorexia nervosa, which is an obsession with healthy and natural foods. The aim of this study was to assess the risk of orthorexia nervosa in patients with IBD. A total of 158 consecutive subjects were recruited, including 113 patients with IBD and 45 controls. The standardized Donini questionnaire ORTO-15 was administered to assess the risk of orthorexia, and clinical and demographic data were collected. The results showed that patients with IBD had a risk of developing orthorexia nervosa of 77%. This was significantly higher than the 47% observed in the control group. In the patients with IBD, the risk of orthorexia was associated with a lower BMI, at least in patients older than 30 years, and it was also associated with marital status in patients younger than 30. In conclusion, many patients with IBD are at increased risk of developing orthorexia nervosa, which may have a negative impact on their psychological wellbeing and social sphere, expose them to a high risk of nutritional deficiencies, and affect their overall quality of life. Further high-quality studies are needed to assess the clinical impact of orthorexia and its correlation with clinical features and classified eating disorders.
炎症性肠病（IBD）患者认为饮食在其疾病的发病机制及症状加重中起着重要作用。他们常常采用限制性饮食，这可能导致营养不良、焦虑和压力。最近的研究发现IBD与饮食失调之间存在关联，如神经性厌食症和回避性限制性食物摄入障碍（ARFID）。这些研究均未报告与对健康天然食物过度痴迷的正食癖有关联。本研究的目的是评估IBD患者中正食癖的风险。共招募了158名连续受试者，包括113例IBD患者和45名对照。采用标准化的多尼尼问卷ORTO - 15来评估正食癖风险，并收集临床和人口统计学数据。结果显示，IBD患者发生正食癖的风险为77%。这显著高于对照组观察到的47%。在IBD患者中，正食癖风险与较低的体重指数相关，至少在30岁以上的患者中如此，并且在30岁以下的患者中还与婚姻状况有关。总之，许多IBD患者发生正食癖的风险增加，这可能对他们的心理健康和社交领域产生负面影响，使他们面临营养缺乏的高风险，并影响他们的整体生活质量。需要进一步开展高质量研究来评估正食癖的临床影响及其与临床特征和分类饮食失调的相关性。
