College of Chemistry, Changchun Normal University, Changchun 130032, China.
College of Chemistry, Changchun Normal University, Changchun 130032, China.
J Hazard Mater. 2024 Jun 5;471:134423. doi: 10.1016/j.jhazmat.2024.134423. Epub 2024 Apr 25.
Phthalate esters (PAEs) are a class of plasticizers that are readily released from plastic products, posing a potential exposure risk to human body. At present, much attention is paid on PAE concentrations in indoor dust with the understanding of PAEs toxicity. This study collected 8187 data on 10 PAEs concentrations in indoor dusts from 26 countries and comprehensively reviewed the worldwide distribution, influencing factors, and health risks of PAEs. Di-(2-ethylhexyl) phthalate (DEHP) is the predominant PAE with a median concentration of 316 μg·g in indoor dust. Polyvinyl chloride wallpaper and flooring and personal care products are the main sources of PAEs indoor dust. The dust concentrations of DEHP show a downward trend over the past two decades, while high dust concentrations of DiNP are found from 2011 to 2016. The median dust contents of 8 PAEs in public places are higher than those in households. Moreover, the concentrations of 9 PAEs in indoor dusts from high-income countries are higher than those from upper-middle-income countries. DEHP in 69.8% and 77.8% of the dust samples may pose a potential carcinogenic risk for adults and children, respectively. Besides, DEHP in 16.9% of the dust samples may pose a non-carcinogenic risk to children. Nevertheless, a negligible risk was found for other PAEs in indoor dust worldwide. This review contributes to an in-depth understanding of the global distribution, sources and health risks of PAEs in indoor dust.
邻苯二甲酸酯(PAEs)是一类容易从塑料制品中释放出来的增塑剂,对人体构成潜在的暴露风险。目前,人们对室内灰尘中 PAEs 浓度的关注度很高,以了解 PAEs 的毒性。本研究收集了来自 26 个国家的 8187 个室内灰尘中 10 种 PAEs 浓度数据,全面综述了全球 PAEs 的分布、影响因素和健康风险。邻苯二甲酸二(2-乙基己基)酯(DEHP)是主要的 PAE,其在室内灰尘中的浓度中位数为 316μg·g。聚氯乙烯壁纸、地板和个人护理产品是室内灰尘中 PAEs 的主要来源。过去 20 年来,DEHP 的灰尘浓度呈下降趋势,而 2011 年至 2016 年发现 DiNP 的灰尘浓度较高。公共场所 8 种 PAEs 的灰尘含量中位数高于家庭。此外,高收入国家室内灰尘中 9 种 PAEs 的浓度高于中上收入国家。69.8%和 77.8%的灰尘样本中的 DEHP 对成人和儿童分别可能构成潜在致癌风险,而 16.9%的灰尘样本中的 DEHP 对儿童可能构成非致癌风险。然而,在全球范围内,室内灰尘中的其他 PAEs 风险可以忽略不计。本综述有助于深入了解全球室内灰尘中 PAEs 的分布、来源和健康风险。