大鼠肠道对铝的吸收

Intestinal absorption of aluminium in rats.

作者信息

van der Voet G B, de Wolff F A

出版信息

Arch Toxicol Suppl. 1985;8:316-8. doi: 10.1007/978-3-642-69928-3_60.

Abstract

To study the mechanism of intestinal aluminium (Al) absorption, an experimental investigation into the uptake of Al from the rat gut was undertaken. The small intestine was perfused in situ for 60 min with isotonic media containing 4.63, 9.25, and 18.50 mmol/l Al chloride at pH 4.0 and 7.0. Portal and systemic blood were sampled and analysed for its Al content by flameless atomic absorption spectrophotometry. It was found that the intestinal absorption of Al in rats is concentration and pH dependent.

摘要

为研究肠道铝（Al）吸收机制，对大鼠肠道铝摄取进行了实验研究。在pH值为4.0和7.0条件下，用含4.63、9.25和18.50 mmol/L氯化铝的等渗介质原位灌注小肠60分钟。采集门静脉血和全身血，采用无火焰原子吸收分光光度法分析其中铝含量。结果发现，大鼠肠道铝吸收与浓度和pH值有关。