Department of Pharmacology, Rajiv Academy for Pharmacy, Mathura, Uttar Pradesh, India.
G.L.A. University, Mathura, Uttar Pradesh, India.
Curr Cardiol Rev. 2024;20(4):e290424229484. doi: 10.2174/011573403X278881240405044328.
Myocardial infarction (MI), also referred to as a "heart attack," is brought on by a partial or total interruption of blood supply to the myocardium. Myocardial infarction can be "silent," go undiagnosed, or it can be a catastrophic occurrence that results in hemodynamic decline and untimely death. In recent years, herbal remedies for MI have become effective, secure, and readily accessible.
The purpose of this review was to examine the medicinal plants and phytochemicals that have been used to treat MI in order to assess the potential contribution of natural substances to the development of herbal MI treatments.
A literature search was employed to find information utilizing electronic databases, such as Web of Science, Google Scholar, PubMed, Sci Finder, Reaxys, and Cochrane.
The identification of 140 plants from 12 families led to the abstraction of data on the plant families, parts of the plant employed, chemical contents, extracts, model used, and dose.
The majority of the MI plants, according to the data, belonged to the Fabaceae (11%) and Asteraceae (9%) families, and the most prevalent natural components in plants with MI were flavonoids (43%), glucosides (25%), alkaloids (23%), phenolic acid (19%), saponins (15%), and tannins (12%).
心肌梗死(MI),也称为“心脏病发作”,是由于心肌供血部分或完全中断引起的。心肌梗死可能是“无症状的”,未被诊断出,也可能是导致血流动力学下降和猝死的灾难性事件。近年来,用于治疗心肌梗死的草药已变得有效、安全且易于获得。
本综述旨在研究用于治疗心肌梗死的药用植物和植物化学物质,以评估天然物质对开发草药治疗心肌梗死的潜在贡献。
采用文献检索的方法,利用电子数据库(如 Web of Science、Google Scholar、PubMed、Sci Finder、Reaxys 和 Cochrane)检索信息。
从 12 个科中鉴定出 140 种植物,从中提取了植物科、植物部位、化学成分、提取物、模型和剂量等数据。
根据数据,大多数心肌梗死植物属于豆科(11%)和菊科(9%),具有心肌梗死作用的植物中最常见的天然成分是黄酮类化合物(43%)、糖苷类(25%)、生物碱(23%)、酚酸(19%)、皂苷(15%)和单宁(12%)。