Pereira Rita, Costa Alexandra, Warkentin Sarah, Vilela Sofia, Oliveira Andreia
EPIUnit - Instituto de Saúde Pública, Universidade Do Porto [Institute of Public Health, University of Porto], Rua Das Taipas, N° 135, 4050-600, Porto, Portugal; Laboratório para a Investigação Integrativa e Translacional Em Saúde Populacional (ITR), Universidade Do Porto, [Laboratory for Integrative and Translational Research in Population Health (ITR), University of Porto], Rua Das Taipas, N° 135, 4050-600, Porto, Portugal.
EPIUnit - Instituto de Saúde Pública, Universidade Do Porto [Institute of Public Health, University of Porto], Rua Das Taipas, N° 135, 4050-600, Porto, Portugal; Laboratório para a Investigação Integrativa e Translacional Em Saúde Populacional (ITR), Universidade Do Porto, [Laboratory for Integrative and Translational Research in Population Health (ITR), University of Porto], Rua Das Taipas, N° 135, 4050-600, Porto, Portugal; Departamento de Saúde Pública e Ciências Forenses e Educação Médica, Faculdade de Medicina, Universidade Do Porto, [Public Health and Forensic Sciences, and Medical Education, Faculty of Medicine, University of Porto], Alameda Prof. Hernâni Monteiro, 4200-319, Porto, Portugal.
Appetite. 2024 Aug 1;199:107384. doi: 10.1016/j.appet.2024.107384. Epub 2024 Apr 28.
Sleep may influence appetite regulation through physiological and neurocognitive pathways. However, the association between sleep and appetite in childhood has been scarcely reported, particularly using a prospective design. We aimed to test associations between sleep duration at 7 years of age (y) and appetitive traits at both 7 and 10 y. Participants are from the population-based birth cohort Generation XXI (Porto, Portugal), at 7 (n = 2437) and 10 y (n = 1938) follow-ups. Data on sleep was gathered at 7 y and, considering bedtime and get-up time, total mean sleep duration was calculated and further categorized according to the 10th and 90th percentiles. Appetitive traits were assessed at 7 and 10 y using the parent-reported Children's Eating Behaviour Questionnaire. Associations were tested through Generalized Linear Models (co-variates: child's sex; maternal age, education and pre-pregnancy body mass index at 7 y). At 10 y, associations were further adjusted for the respective appetitive trait at 7 y. Children slept a mean of 10.2 h/night, and 13% and 9% slept ≤9.5 and ≥ 11.0 h/night at 7 y, respectively. For each additional hour in sleep duration, children scored 0.078 (99%CI: -0.145; -0.011) lower on Food Responsiveness, 0.065 (99%CI: -0.129; -0.002) lower on Emotional Undereating and 0.096 (99%CI: -0.161; -0.032) lower on Food Fussiness. Lastly, children sleeping ≤9.5 h/night scored higher on Food Responsiveness (β = 0.145 99%CI: 0.020; 0.271); while those sleeping ≥11.0 h/night scored lower on Food Fussiness (β = -0.255 99%CI: -0.370; -0.079). No significant prospective associations were found. In conclusion, in 7 y children, sleep duration was cross-sectionally associated with lower scores on food approach (Food Responsiveness) and avoidant traits (Emotional Undereating and Food Fussiness). However, the magnitude of the associations was small and further studies are warranted.
睡眠可能通过生理和神经认知途径影响食欲调节。然而，儿童期睡眠与食欲之间的关联鲜有报道，尤其是采用前瞻性设计的研究。我们旨在测试7岁时的睡眠时间与7岁和10岁时的食欲特征之间的关联。研究对象来自葡萄牙波尔图基于人群的二十一世纪出生队列，分别进行7岁（n = 2437）和10岁（n = 1938）的随访。在7岁时收集睡眠数据，根据就寝时间和起床时间计算总平均睡眠时间，并进一步按照第10和第90百分位数进行分类。在7岁和10岁时使用家长报告的儿童饮食行为问卷评估食欲特征。通过广义线性模型测试关联（协变量：儿童性别；母亲年龄、教育程度以及7岁时的孕前体重指数）。在10岁时，关联进一步根据7岁时各自的食欲特征进行调整。儿童平均每晚睡眠10.2小时，7岁时分别有13%和9%的儿童睡眠≤9.5小时和≥11.0小时。睡眠时间每增加一小时，儿童在食物反应性方面得分降低0.078（99%置信区间：-0.145；-0.011），在情绪性饮食不足方面得分降低0.065（99%置信区间：-0.129；-0.002），在食物挑剔方面得分降低0.096（99%置信区间：-0.161；-0.032）。最后，每晚睡眠≤9.5小时的儿童在食物反应性方面得分较高（β = 0.145，99%置信区间：0.020；0.271）；而每晚睡眠≥11.0小时的儿童在食物挑剔方面得分较低（β = -0.255，99%置信区间：-0.370；-0.079）。未发现显著的前瞻性关联。总之，对于7岁儿童，睡眠时间与食物趋近（食物反应性）得分较低以及回避特征（情绪性饮食不足和食物挑剔）存在横断面关联。然而，这些关联的程度较小，需要进一步研究。
