Manjunath K N, Kulkarni Anjali, Kulkarni Vamshikrishna
Department of Computer Science and Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Consultant in Radiation Oncology, Clinical Informatics and Artificial Intelligence, Karkinos Healthcare, Bengaluru, India.
Cardiovasc Eng Technol. 2024 Aug;15(4):383-393. doi: 10.1007/s13239-024-00715-4. Epub 2024 Apr 30.
Cardiac CT is a valuable diagnostic tool in evaluating cardiovascular diseases. Accurate segmentation of the heart and its structures from cardiac CT and MRI images is essential for diagnosing functional abnormalities, treatment plans and cardiovascular diseases management. Accurate segmentation and quantitative assessments are still a challenge. Manual delineation of the heart from the scan images is labour-intensive, time-consuming, and error prone as it depends on the radiologist's experience. Thus, automated techniques are highly desirable as they can significantly improve the efficiency and accuracy of image analysis.
This work addresses the above problems. A new, image-driven, fast, and fully automatic segmentation method was developed to segment the heart from CT images using a processing pipeline of adaptive median filter, multi-level thresholding, active contours, mathematical morphology, and the knowledge of human anatomy to delineate the regions of interest.
The algorithm proposed is simple to implement and validate and requires no human intervention. The method is tested on the 'Image CHD' DICOM images (multi-centre, clinically approved single-phase de-identified images), and the results obtained were validated against the ground truths provided with the dataset. The results show an average Dice score, Jaccard score, and Hausdorff distance of 0.866, 0.776, and 33.29 mm, respectively, for the segmentation of the heart's chambers, aorta, and blood vessels. The results and the ground truths were compared using Bland-Altmon plots.
The heart was correctly segmented from the CT images using the proposed method. Further this segmentation technique can be used to develop AI based solutions for segmentation.
心脏CT是评估心血管疾病的一种有价值的诊断工具。从心脏CT和MRI图像中准确分割心脏及其结构对于诊断功能异常、制定治疗方案和管理心血管疾病至关重要。准确的分割和定量评估仍然是一个挑战。通过扫描图像手动描绘心脏既费力、耗时,又容易出错,因为这取决于放射科医生的经验。因此,非常需要自动化技术,因为它们可以显著提高图像分析的效率和准确性。
这项工作解决了上述问题。开发了一种新的、图像驱动的、快速且全自动的分割方法,使用自适应中值滤波器、多级阈值处理、活动轮廓、数学形态学以及人体解剖学知识的处理流程从CT图像中分割心脏,以描绘感兴趣区域。
所提出的算法易于实现和验证,无需人工干预。该方法在“Image CHD”DICOM图像(多中心、临床批准的单相去识别图像)上进行了测试,所得结果与数据集提供的地面真值进行了验证。结果显示,对于心脏腔室、主动脉和血管的分割,平均Dice分数、Jaccard分数和豪斯多夫距离分别为0.866、0.776和33.29毫米。使用Bland-Altmon图对结果和地面真值进行了比较。
使用所提出的方法从CT图像中正确分割出了心脏。此外,这种分割技术可用于开发基于人工智能的分割解决方案。