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伪装成类风湿关节炎的结节性红斑麻风反应

Erythema Nodosum Leprosum Reaction Masquerading as Rheumatoid Arthritis.

作者信息

Deo Kirti, Reddy Aravind, Manoj Rohan, Singh Shrishti

机构信息

Dermatology, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.

出版信息

Cureus. 2024 Mar 31;16(3):e57312. doi: 10.7759/cureus.57312. eCollection 2024 Mar.

DOI:10.7759/cureus.57312
PMID:38690488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11059848/
Abstract

Erythema nodosum leprosum is a type 3 hypersensitivity reaction that often presents with transient eruptions of red papules, plaques, and nodules. A 52-year-old female presented with multiple joint pain that was being treated as rheumatoid arthritis (RA), but through clinical examination, she was found to have Hansen's disease with a type 2 reaction. Hence, the importance of a thorough clinical examination is a must for the timely and correct diagnosis of patients suffering from Hansen's disease.

摘要

结节性红斑麻风是一种Ⅲ型超敏反应，常表现为红色丘疹、斑块和结节的短暂性皮疹。一名52岁女性因多关节疼痛就诊，最初被诊断为类风湿关节炎（RA），但通过临床检查，发现她患的是2型反应的汉森病。因此，对于及时、正确诊断汉森病患者而言，全面的临床检查至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f34/11059848/87828b59bafe/cureus-0016-00000057312-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f34/11059848/5ded52b14579/cureus-0016-00000057312-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f34/11059848/a81c0e8d2d06/cureus-0016-00000057312-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f34/11059848/87828b59bafe/cureus-0016-00000057312-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f34/11059848/5ded52b14579/cureus-0016-00000057312-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f34/11059848/a81c0e8d2d06/cureus-0016-00000057312-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f34/11059848/87828b59bafe/cureus-0016-00000057312-i03.jpg

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本文引用的文献

1
A challenging case of rheumatoid arthritis-associated aortitis presenting with erythema nodosum after ST-segment elevation myocardial infarction: A case report.1例类风湿关节炎相关性主动脉炎在ST段抬高型心肌梗死后出现结节性红斑的具有挑战性病例：病例报告
Clin Case Rep. 2022 Nov 12;10(11):e6402. doi: 10.1002/ccr3.6402. eCollection 2022 Nov.
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Leprosy: clinical and immunopathological characteristics.麻风病：临床和免疫病理学特征。
An Bras Dermatol. 2022 May-Jun;97(3):338-347. doi: 10.1016/j.abd.2021.08.006. Epub 2022 Apr 2.
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Leprosy: Treatment and management of complications.
麻风病：并发症的治疗与管理。
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Leprosy: Clinical aspects and diagnostic techniques.麻风病：临床方面与诊断技术。
J Am Acad Dermatol. 2020 Jul;83(1):1-14. doi: 10.1016/j.jaad.2019.12.080. Epub 2020 Mar 27.
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Position statement: LEPROSY: Diagnosis, treatment and follow-up.立场声明：麻风病：诊断、治疗和随访。
J Eur Acad Dermatol Venereol. 2019 Jul;33(7):1205-1213. doi: 10.1111/jdv.15569. Epub 2019 Apr 3.
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Leprosy - an overview of clinical features, diagnosis, and treatment.麻风病——临床特征、诊断和治疗概述。
J Dtsch Dermatol Ges. 2017 Aug;15(8):801-827. doi: 10.1111/ddg.13301.
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Histopathology of the lepromatous skin biopsy.麻风性皮肤活检的组织病理学
Clin Dermatol. 2015 Jan-Feb;33(1):38-45. doi: 10.1016/j.clindermatol.2014.10.003.
8
Leprosy and rheumatoid arthritis: consequence or association?麻风病与类风湿性关节炎：是结果还是关联？
BMJ Case Rep. 2012 Aug 13;2012:bcr1220115346. doi: 10.1136/bcr.12.2011.5346.
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Arthritis in leprosy.麻风性关节炎。
Rheumatology (Oxford). 2010 Dec;49(12):2237-42. doi: 10.1093/rheumatology/keq264. Epub 2010 Aug 19.
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Protective effect of the combination BCG vaccination and rifampicin prophylaxis in leprosy prevention.卡介苗接种和利福平预防在麻风病预防中的保护作用。
Vaccine. 2009 Nov 23;27(50):7125-8. doi: 10.1016/j.vaccine.2009.09.054. Epub 2009 Sep 26.