建立并验证了一种高效薄层色谱法，用于检测膳食补充剂中的西布曲明。
Development and validation of a high-performance thin-layer chromatography method for detection of sibutramine in dietary supplements.
机构信息
Medical University of Plovdiv, Plovdiv, Bulgaria.
出版信息
Folia Med (Plovdiv). 2024 Apr 30;66(2):255-263. doi: 10.3897/folmed.66.e121218.
PMID:38690822
Abstract
In the period between 1997 and 2010, sibutramine-containing drugs were widely prescribed for obesity and over-weight management. Due to safety concerns, in 2010 all medicines containing sibutramine were urgently withdrawn from the USA and European pharmaceutical market. Although sibutramine is no longer available in pharmaceutical products, there have been numerous reports of mislabeled weight-loss dietary supplements containing sibutramine.
摘要
在 1997 年至 2010 年期间，含有西布曲明的药物被广泛用于治疗肥胖症和超重。由于安全性问题，2010 年所有含有西布曲明的药物都被紧急撤出美国和欧洲药品市场。尽管西布曲明已不再作为药品使用，但仍有大量含有西布曲明的标签有误的减肥膳食补充剂的报告。
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