Division of Pharmaceutics and Pharmacokinetics, Central Drug Research Institute, Council of Scientific and Industrial Research, Lucknow 226031, Uttar Pradesh, India; Academy of Scientific and Innovative Research, Ghaziabad 201002, Uttar Pradesh, India.
Division of Pharmaceutics and Pharmacokinetics, Central Drug Research Institute, Council of Scientific and Industrial Research, Lucknow 226031, Uttar Pradesh, India.
J Integr Med. 2024 Jul;22(4):385-398. doi: 10.1016/j.joim.2024.04.005. Epub 2024 Apr 24.
Phytosomes (phytophospholipid complex) are dosage forms that have recently been introduced to increase the stability and therapeutic effect of herbal medicine. Currently, bioactive herbs and the phytochemicals they contain are considered to be the best remedies for chronic diseases. One promising approach to increase the efficacy of plant-based therapies is to improve the stability and bioavailability of their bio-active ingredients. Phytosomes employ phospholipids as their active ingredients, and use their amphiphilic properties to solubilize and protect herbal extracts. The unique properties of phospholipids in drug delivery and their use in herbal medicines to improve bioavailability results in significantly enhanced health benefits. The introduction of phytosome nanotechnology can alter and revolutionize the current state of drug delivery. The goal of this review is to explain the application of phytosomes, their future prospects in drug delivery, and their advantages over conventional formulations. Please cite this article as: Chauhan D, Yadav PK, Sultana N, Agarwal A, Verma S, Chourasia MK, Gayen JR. Advancements in nanotechnology for the delivery of phytochemicals. J Integr Med. 2024; 22(4): 385-398.
植物磷脂体（植物磷脂复合物）是最近引入的剂型，旨在提高草药的稳定性和治疗效果。目前，生物活性草药及其所含的植物化学物质被认为是治疗慢性病的最佳药物。提高植物疗法疗效的一种有前途的方法是提高其生物活性成分的稳定性和生物利用度。植物磷脂体采用磷脂作为其活性成分，并利用其两亲性质来溶解和保护草药提取物。磷脂在药物传递中的独特性质及其在草药中的应用可提高生物利用度，从而显著增强健康益处。植物磷脂体纳米技术的引入可以改变和彻底改变目前的药物传递状态。本综述的目的是解释植物磷脂体的应用、它们在药物传递中的未来前景以及它们相对于传统制剂的优势。请引用本文作为：Chauhan D, Yadav PK, Sultana N, Agarwal A, Verma S, Chourasia MK, Gayen JR. 纳米技术在植物化学物质传递中的应用。综合医学杂志。2024; 22(4): 385-398.
