Rahman Nafiur, Gope Arpita, Khanrah Jayeeta, Rawani Anjali
Laboratory of Parasitology, Vector Biology, Nanotechnology, Department of Zoology, The University of Gour Banga, Malda, West Bengal, 732103, India.
Curr Drug Discov Technol. 2025;22(2):e300424229557. doi: 10.2174/0115701638294753240422134722.
Insects are the most numerous and diverse collection of organisms on earth. Around the world, human societies have utilised insects and the materials derived from them as medical resources. These arthropods use chemistry, like all other species. According to their survival needs, they make adaptations, including protecting themselves from infection as well as predation, being able to connect with a social life, and carrying out generations with survivability in the environment. The main focus of the study of chemical ecology is the abundance of chemical compounds found in arthropods that are used for these ecological adaptations. This thorough analysis summarises the huge potential for finding new natural compounds with medical benefits from the Arthropods. Insects and their derivatives have a wide range of uses, and their "raw products" have made significant strides in a wide range of industries, including pharmaceuticals, tissue engineering, dentistry, plant and agricultural science, veterinary medicine, cosmetics, and cosmeceuticals, food, and nutraceuticals, among others. Bioactive components derived from insects are emerging as potential therapeutic sources that are beneficial against a variety of disorders. Insects, which have a huge variety of species, are an intriguing and potential source of low molecular biologically active natural compounds that are either produced by the insect itself or by accompanying microbes. The present review work collated the updates of insect-derived compounds, the use of insects worldwide, and drug discovery potential of insect derivatives.
昆虫是地球上数量最多、种类最丰富的生物群体。在世界各地，人类社会一直将昆虫及其衍生材料用作医疗资源。与所有其他物种一样，这些节肢动物利用化学物质。根据它们的生存需求，它们会做出适应性改变，包括保护自己免受感染和捕食、能够融入社会生活以及在环境中繁衍后代并具备生存能力。化学生态学研究的主要重点是节肢动物中发现的用于这些生态适应的大量化合物。这项全面分析总结了从节肢动物中发现具有医疗益处的新天然化合物的巨大潜力。昆虫及其衍生物有广泛的用途，它们的“原材料”在包括制药、组织工程、牙科、植物与农业科学、兽医学、化妆品和药妆品、食品和营养保健品等众多行业都取得了重大进展。源自昆虫的生物活性成分正成为对抗多种疾病的潜在治疗来源。昆虫种类繁多，是一种有趣且有潜力的低分子生物活性天然化合物来源，这些化合物要么由昆虫自身产生，要么由伴生微生物产生。本综述工作整理了昆虫衍生化合物的最新情况、昆虫在全球的用途以及昆虫衍生物的药物发现潜力。
