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感染艾滋病毒/艾滋病儿童的发育迟缓及其相关因素:一项横断面研究。

Stunting and its associated factors among children living with HIV/AIDS: a cross-sectional study.

作者信息

Dagnew Zewdu, Mengist Zeleke, Tesema Cheru, Temesgen Tegegne, Kumlachew Lake, Teym Abraham, Yirdaw Getasew, Bewket Yenewa, Addisie Zemene, Ayele Kemachew, Ayele Agernesh, Adane Balew, Tegegne Eniyew

机构信息

Departments of Environmental Health.

Public Health.

出版信息

Ann Med Surg (Lond). 2024 Mar 18;86(5):2579-2585. doi: 10.1097/MS9.0000000000001961. eCollection 2024 May.

Abstract

BACKGROUND

Growth failure is a common feature of children living with HIV/AIDS. This study was intended to assess the level of stunting and its associated factors among children living with HIV/AIDS.

METHODS

An institution-based cross-sectional study was conducted among 218 children living with HIV/AIDS. An interviewer-administered data collection tools and anthropometric measurements were used to collect data. Bivariable and multivariable logistic regression analyses were used to identify independent variables. Adjusted odds ratio with a 95% CI at a value of 0.05, which was considered to declare statistical significance.

RESULT

The level of stunting among children infected with HIV/AIDS in selected northwest comprehensive specialized hospitals in western Amhara was 56.9%. Poor anti-retroviral therapy (ART) adherence [adjusted odds ratio (AOR)=6.15, 95% CI, (3.88-9.69)], lack of co-trimoxazole prophylaxis [AOR=2.0, 95% CI, (1.88-2.98)], opportunistic infection [AOR=4.66, 95% CI, (3.24-6.11), and feeding twice [AOR=3.88, 95% CI, (1.94-5.14)] and feeding three times [AOR=1.52, 95% CI, (1.23-3.89)] were significantly associated with stunting.

CONCLUSION

Stunting among HIV/AIDS-infected children was very high. Poor ART adherence, lack of co-trimoxazole prophylaxis, opportunistic infection, and low feeding frequency were significantly associated to stunting among HIV/AIDS-infected children. Strategies need to be devised to address factors amenable to modification to improve the growth of children living with HIV/AIDS.

摘要

背景

生长发育迟缓是感染艾滋病毒/艾滋病儿童的常见特征。本研究旨在评估感染艾滋病毒/艾滋病儿童的发育迟缓水平及其相关因素。

方法

在218名感染艾滋病毒/艾滋病儿童中开展了一项基于机构的横断面研究。使用由访谈员实施的数据收集工具和人体测量方法收集数据。采用双变量和多变量逻辑回归分析来确定独立变量。调整后的优势比及95%置信区间,以P值0.05来判定统计学显著性。

结果

在阿姆哈拉西部选定的西北综合专科医院中,感染艾滋病毒/艾滋病儿童的发育迟缓水平为56.9%。抗逆转录病毒疗法(ART)依从性差[调整后的优势比(AOR)=6.15,95%置信区间,(3.88 - 9.69)]、未进行复方新诺明预防[ AOR = 2.0,95%置信区间,(1.88 - 2.98)]、机会性感染[ AOR = 4.66,95%置信区间,(3.24 - 6.11)],以及每日喂食两次[ AOR = 3.88,95%置信区间,(1.94 - 5.14)]和每日喂食三次[ AOR = 1.52,95%置信区间,(1.23 - 3.89)]均与发育迟缓显著相关。

结论

感染艾滋病毒/艾滋病儿童的发育迟缓情况非常严重。抗逆转录病毒疗法依从性差、未进行复方新诺明预防、机会性感染和喂食频率低与感染艾滋病毒/艾滋病儿童的发育迟缓显著相关。需要制定策略来解决可改变的因素,以改善感染艾滋病毒/艾滋病儿童的生长发育状况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ec9/11060262/9eab4a7be846/ms9-86-2579-g001.jpg

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