Ghafouri Abdullah M, Alzaidi Suzan, Al-Kaabi Bader B, Awadh Mohammed A, Bakhsh Dohaa, Alharbi Abdullah
Department of Otolaryngology, Head and Neck Surgery, King Fahad Armed Forces Hospital, Jeddah, SAU.
College of Medicine, Umm Al-Qura University, Makkah, SAU.
Cureus. 2024 Mar 31;16(3):e57359. doi: 10.7759/cureus.57359. eCollection 2024 Mar.
Primary thyroid lymphoma (PTL) is a rare type of thyroid cancer, comprising less than 5% of all thyroid cancer cases. PTL includes subtypes like diffuse large B-cell lymphoma (DLBCL) and mucosa-associated lymphoid tissue lymphoma (MALT). The connection between PTL and autoimmune diseases of the thyroid, particularly Hashimoto's thyroiditis, has gained recognition in recent years. Studies have indicated an increased incidence of PTL among individuals with Hashimoto's thyroiditis. However, effectively recognizing and managing PTL in the context of autoimmune thyroid diseases remains challenging. Further research and clinical experience are needed to develop comprehensive strategies for early detection and optimal management of this complex condition. In a case involving an 88-year-old female diagnosed with diffuse large B-cell lymphoma, she presented with a complaint of persistent neck swelling for five years. The patient also experienced symptoms such as dysphagia, hoarseness of voice, obstructive sleep apnea, and choking attacks. Surgical resection of the neck swelling was successfully performed, and the patient was referred to the oncology department for further treatment. Thyroid B-cell lymphoma is an exceedingly rare form of thyroid cancer, typically identified in individuals who have a history of Hashimoto's thyroiditis. The prognosis for thyroid B-cell lymphoma is generally unfavorable, and surgical intervention remains the primary treatment approach for such cases.
原发性甲状腺淋巴瘤（PTL）是一种罕见的甲状腺癌类型，占所有甲状腺癌病例的比例不到5%。PTL包括弥漫性大B细胞淋巴瘤（DLBCL）和黏膜相关淋巴组织淋巴瘤（MALT）等亚型。近年来，PTL与甲状腺自身免疫性疾病，尤其是桥本甲状腺炎之间的联系已得到认可。研究表明，桥本甲状腺炎患者中PTL的发病率有所增加。然而，在自身免疫性甲状腺疾病的背景下有效识别和管理PTL仍然具有挑战性。需要进一步的研究和临床经验来制定针对这种复杂病症的早期检测和最佳管理的综合策略。在一个病例中，一名88岁女性被诊断为弥漫性大B细胞淋巴瘤，她主诉颈部持续肿胀五年。患者还出现了吞咽困难、声音嘶哑、阻塞性睡眠呼吸暂停和窒息发作等症状。颈部肿胀的手术切除成功进行，患者被转诊至肿瘤科进行进一步治疗。甲状腺B细胞淋巴瘤是一种极其罕见的甲状腺癌形式，通常在有桥本甲状腺炎病史的个体中发现。甲状腺B细胞淋巴瘤的预后通常不佳，手术干预仍然是此类病例的主要治疗方法。
