Li Peiyun, Sun Wenxi, Li Jiulong, Chen Ju-Peng, Wang Xinyue, Mei Zi, Jin Guanyu, Lei Yuqiu, Xin Ruiyun, Yang Mo, Xu Jingcao, Pan Xiran, Song Cheng, Deng Xin-Yu, Lei Xun, Liu Kai, Wang Xiu, Zheng Yuting, Zhu Jia, Lv Shixian, Zhang Zhi, Dai Xiaochuan, Lei Ting
Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, School of Materials Science and Engineering, Peking University, Beijing 100871, China.
Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China.
Science. 2024 May 3;384(6695):557-563. doi: 10.1126/science.adj4397. Epub 2024 May 2.
Hydrogels are an attractive category of biointerfacing materials with adjustable mechanical properties, diverse biochemical functions, and good ionic conductivity. Despite these advantages, their application in electronics has been restricted because of their lack of semiconducting properties, and they have traditionally only served as insulators or conductors. We developed single- and multiple-network hydrogels based on a water-soluble n-type semiconducting polymer, endowing conventional hydrogels with semiconducting capabilities. These hydrogels show good electron mobilities and high on/off ratios, enabling the fabrication of complementary logic circuits and signal amplifiers with low power consumption and high gains. We demonstrate that hydrogel electronics with good bioadhesive and biocompatible interface can sense and amplify electrophysiological signals with enhanced signal-to-noise ratios.
水凝胶是一类具有吸引力的生物界面材料，具有可调节的机械性能、多样的生化功能和良好的离子导电性。尽管具有这些优点，但由于缺乏半导体特性，它们在电子领域的应用受到了限制，传统上仅用作绝缘体或导体。我们基于水溶性n型半导体聚合物开发了单网络和多网络水凝胶，赋予传统水凝胶半导体能力。这些水凝胶表现出良好的电子迁移率和高开关比，能够制造出具有低功耗和高增益的互补逻辑电路和信号放大器。我们证明，具有良好生物粘附性和生物相容性界面的水凝胶电子器件能够以更高的信噪比感知和放大电生理信号。
