Department of Clinical Pharmacy and Biopharmacy, University of Uyo, Nigeria.
Department of Clinical Pharmacy and Pharmacy Management, University of Nigeria, Nsukka, Nigeria.
Epilepsy Res. 2021 Aug;174:106648. doi: 10.1016/j.eplepsyres.2021.106648. Epub 2021 Apr 27.
The impact of epilepsy on the quality of life of the patient can be considerably high with far-reaching and life-long consequences. The goal of patient counseling and education is to achieve positive clinical outcomes and optimize the patient's health-related quality of life.
To evaluate the impact of a pharmacist-led education and counselling interventions on the health-related quality of life of patients living with epilepsy.
A randomized controlled trial was carried out on epilepsy patients attending the neurology/medical out-patient clinics of two tertiary hospitals. Patients in the intervention group were offered education and counselling services. The impact of the interventions on the patients' quality of life in epilepsy was evaluated using the QOLIE-10P questionnaire. The research protocol was approved by the Health Research Ethics Committees of the University of Uyo Teaching Hospital and University of Calabar Teaching Hospital (Reference numbers: UUTH/AD/S/96/VOL.XIV/571 & UCTH/HREC/33/454).
There was a statistically significant difference between the usual care (UC) and the pharmaceutical care (PC) group on the quality of life in epilepsy scores post-intervention. Comparisons between groups (UC versus PC) revealed that patients in the PC group had a significantly higher QOLIE score than those in the UC group at 3 months and 6 months - (Pre-intervention: 8.73 versus 7.91; t = 0.619; p = 0.537), (3 months: 9.74 versus 15.37; t = -3.34; p = 0.01), (6 months: 11.59 versus 17.01; t = -3.137; p = 0.01).
Pharmacist-led education and counselling interventions may significantly improve the quality of life of patients with epilepsy.
癫痫对患者生活质量的影响可能相当大，具有深远且终身的影响。患者咨询和教育的目标是实现积极的临床结果并优化患者的健康相关生活质量。
评估药剂师主导的教育和咨询干预对患有癫痫的患者健康相关生活质量的影响。
对两家三级医院神经科/内科门诊就诊的癫痫患者进行了一项随机对照试验。干预组患者提供教育和咨询服务。使用 QOLIE-10P 问卷评估干预对患者癫痫生活质量的影响。该研究方案获得了 Uyo 教学医院和卡拉巴尔教学医院的健康研究伦理委员会的批准（参考编号：UUTH/AD/S/96/VOL.XIV/571 和 UCTH/HREC/33/454）。
干预后，常规护理（UC）和药物护理（PC）组在癫痫生活质量评分方面存在统计学显著差异。组间比较（UC 与 PC）显示，PC 组患者的 QOLIE 评分明显高于 UC 组，分别为 3 个月和 6 个月时-（干预前：8.73 与 7.91；t=0.619；p=0.537），（3 个月：9.74 与 15.37；t=-3.34；p=0.01），（6 个月：11.59 与 17.01；t=-3.137；p=0.01）。
药剂师主导的教育和咨询干预可能显著改善癫痫患者的生活质量。
