Shi Lvyuan, Wang Bo, Wu Qin, Yang Jing, Wang Lietao, Wan Dingyuan, Wang Yucong, Feng Zhongxue, Zhang Wei, Li Li, Wang Wenhu, Chen Jun, Ai Xiaohua, Zheng Jianwei, Zhang Zhongwei, He Min
Department of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Department of State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, China.
Front Public Health. 2024 Apr 17;12:1349753. doi: 10.3389/fpubh.2024.1349753. eCollection 2024.
An increase in Heatstroke cases occurred in southwest China in 2022 due to factors like global warming, abnormal temperature rise, insufficient power supply, and other contributing factors. This resulted in a notable rise in Heatstroke patients experiencing varying degrees of organ dysfunction. This descriptive study aims to analyze the epidemiology and clinical outcomes of Heatstroke patients in the ICU, providing support for standardized diagnosis and treatment, ultimately enhancing the prognosis of Heatstroke.
A retrospective, multicenter, descriptive analysis was conducted on Heatstroke patients admitted to ICUs across 83 hospitals in southwest China. Electronic medical records were utilized for data collection, encompassing various aspects such as epidemiological factors, onset symptoms, complications, laboratory data, concurrent infections, treatments, and patient outcomes.
The dataset primarily comprised classic heatstroke, with 477 males (55% of total). The patient population had a median age of 72 years (range: 63-80 years). The most common initial symptoms were fever, mental or behavioral abnormalities, and fainting. ICU treatment involved respiratory support, antibiotics, sedatives, and other interventions. Among the 700 ICU admissions, 213 patients had no infection, while 487 were diagnosed with infection, predominantly lower respiratory tract infection. Patients presenting with neurological symptoms initially ( = 715) exhibited higher ICU mortality risk compared to those without neurological symptoms ( = 104), with an odds ratio of 2.382 (95% CI 1.665, 4.870) ( = 0.017).
In 2022, the majority of Heatstroke patients in southwest China experienced classical Heatstroke, with many acquiring infections upon admission to the ICU. Moreover, Heatstroke can result in diverse complications.
2022年，由于全球变暖、气温异常升高、电力供应不足等因素，中国西南部中暑病例有所增加。这导致中暑患者出现不同程度器官功能障碍的情况显著增多。本描述性研究旨在分析重症监护病房（ICU）中暑患者的流行病学特征及临床结局，为标准化诊断和治疗提供支持，最终改善中暑的预后。
对中国西南部83家医院ICU收治的中暑患者进行回顾性、多中心、描述性分析。利用电子病历收集数据，涵盖流行病学因素、起病症状、并发症、实验室数据、合并感染、治疗及患者结局等各个方面。
数据集主要包括经典中暑病例，男性477例（占总数的55%）。患者人群的中位年龄为72岁（范围：63 - 80岁）。最常见的初始症状为发热、精神或行为异常以及昏厥。ICU治疗包括呼吸支持、抗生素、镇静剂及其他干预措施。在700例入住ICU的患者中，213例无感染，487例被诊断为感染，主要为下呼吸道感染。初始表现为神经症状的患者（n = 715）与无神经症状的患者（n = 104）相比，ICU死亡风险更高，优势比为2.382（95%可信区间1.665, 4.870）（P = 0.017）。
2022年，中国西南部大多数中暑患者为经典中暑，许多患者在入住ICU时发生感染。此外，中暑可导致多种并发症。
