人类产乙醇微生物目录。
A catalog of ethanol-producing microbes in humans.
机构信息
Aix Marseille Université, AP-HM, MEPHI, Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France.
Department of Hepatology, La Timone University Hospital, AP-HM, Marseille, France.
出版信息
Future Microbiol. 2024;19(8):697-714. doi: 10.2217/fmb-2023-0250. Epub 2024 May 3.
Endogenous ethanol production emerges as a mechanism of nonalcoholic steatohepatitis, obesity, diabetes and auto-brewery syndrome. To identify ethanol-producing microbes in humans, we used the NCBI taxonomy browser and the PubMed database with an automatic query and manual verification. 85 ethanol-producing microbes in human were identified. , and were the most represented fungi. Enterobacteriaceae was the most represented bacterial family with mainly and . Species of the Lachnospiraceae and Clostridiaceae family, of the Lactobacillales order and of the genus were also identified. This catalog will help the study of ethanol-producing microbes in human in the pathophysiology, diagnosis, prevention and management of human diseases associated with endogenous ethanol production.
内源性乙醇产生是导致非酒精性脂肪性肝炎、肥胖、糖尿病和自酿综合征的一种机制。为了鉴定人体内产生乙醇的微生物，我们使用了 NCBI 分类浏览器和 PubMed 数据库，采用自动查询和手动验证相结合的方法。鉴定出了 85 种人类产乙醇微生物。真菌中以 、 和 最为常见。肠杆菌科是最主要的细菌家族，主要包括 和 。还鉴定出了梭菌科和lachnospiraceae 科、乳杆菌目和 属的物种。该目录将有助于研究与内源性乙醇产生相关的人类疾病的病理生理学、诊断、预防和管理中乙醇产生微生物。
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