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光子计数 CT 技术用于儿科先天性心脏病,在 70kV 和 90kV 时均可实现低剂量、高质量的图像诊断。

Photon-counting computed tomography for paediatric congenital heart defects yields images of high diagnostic quality with low radiation doses at both 70 kV and 90 kV.

机构信息

Diagnostic Radiology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.

Department of Radiology, Skåne University Hospital, S-22185, Lund, Sweden.

出版信息

Pediatr Radiol. 2024 Jun;54(7):1187-1196. doi: 10.1007/s00247-024-05939-z. Epub 2024 May 3.

DOI:10.1007/s00247-024-05939-z
PMID:38700554
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11182870/
Abstract

BACKGROUND

Photon-counting computed tomography (PCCT) is a new clinical method that may show better diagnostic quality at lower radiation doses than conventional CT.

OBJECTIVE

To investigate the diagnostic quality and radiation dose of paediatric cardiovascular PCCT for diagnosis of congenital heart defects at 70 kV and 90 kV.

MATERIALS AND METHODS

This retrospective assessment included clinical non-gated paediatric PCCT examinations for assessment of congenital heart defects. Radiation doses were recorded, and overall and specific diagnostic quality (1-4) were scored by four paediatric radiologists. Agreement, differences, and trends were assessed by percent rater agreement, intraclass correlation, Mann-Whitney tests, and Jonckheere-Terpstra tests.

RESULTS

Seventy children with congenital heart defects were examined at 70 kV (n = 35; age 2 days-16 years; 63% boys) or 90 kV (n = 35; age 2 days-17 years; 51% boys). All observers gave a median score of 4 (high diagnostic quality) for both 70 kV and 90 kV, with no difference in median values between tube voltages (all P > 0.06). Agreement for overall scores was 66-94% for 70 kV and 60-77% for 90 kV. Agreement for specific scores was 80-97% for 70 kV and 83-89% for 90 kV. Size-dependent dose estimate was 0.68 mGy (0.25-2.02 mGy) for 70 kV and 1.10 mGy (0.58-2.71 mGy; P < 0.001) for 90 kV. Effective dose was 0.30 mSv (0.15-0.82 mSv) for 70 kV and 0.39 mSv (0.22-1.51 mSv; P = 0.01) for 90 kV.

CONCLUSION

Paediatric cardiovascular PCCT yields images for congenital heart defects of high diagnostic quality with low radiation dose at both 70 kV and 90 kV.

摘要

背景

光子计数计算机断层扫描(PCCT)是一种新的临床方法,与常规 CT 相比,它可能在更低的辐射剂量下显示出更好的诊断质量。

目的

探讨 70kV 和 90kV 管电压下用于诊断先天性心脏病的儿科心血管 PCCT 的诊断质量和辐射剂量。

材料和方法

本回顾性评估纳入了用于评估先天性心脏病的临床非门控儿科 PCCT 检查。记录辐射剂量,由 4 名儿科放射科医生对整体和特定诊断质量(1-4 分)进行评分。通过百分比评分者一致性、组内相关系数、Mann-Whitney 检验和 Jonckheere-Terpstra 检验评估一致性、差异和趋势。

结果

70 例患有先天性心脏病的儿童在 70kV(n=35;年龄 2 天-16 岁;63%为男孩)或 90kV(n=35;年龄 2 天-17 岁;51%为男孩)下接受检查。所有观察者对 70kV 和 90kV 的中位数评分为 4(高诊断质量),管电压之间的中位数值无差异(均 P>0.06)。70kV 的整体评分一致性为 66%-94%,90kV 的整体评分一致性为 60%-77%。70kV 的特定评分一致性为 80%-97%,90kV 的特定评分一致性为 83%-89%。70kV 的剂量估计值与体型相关,为 0.68mGy(0.25-2.02mGy),90kV 的剂量估计值为 1.10mGy(0.58-2.71mGy;P<0.001)。70kV 的有效剂量为 0.30mSv(0.15-0.82mSv),90kV 的有效剂量为 0.39mSv(0.22-1.51mSv;P=0.01)。

结论

70kV 和 90kV 下,用于诊断先天性心脏病的儿科心血管 PCCT 可获得高质量的图像,辐射剂量低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f9e/11182870/cd749d7e5211/247_2024_5939_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f9e/11182870/aa88be6191ce/247_2024_5939_Fig1_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f9e/11182870/b2202d24c666/247_2024_5939_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f9e/11182870/ad2b811aab1c/247_2024_5939_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f9e/11182870/cd749d7e5211/247_2024_5939_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f9e/11182870/aa88be6191ce/247_2024_5939_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f9e/11182870/1c80d7dd274b/247_2024_5939_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f9e/11182870/1e89cfe0a4c5/247_2024_5939_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f9e/11182870/b2202d24c666/247_2024_5939_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f9e/11182870/ad2b811aab1c/247_2024_5939_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f9e/11182870/cd749d7e5211/247_2024_5939_Fig6_HTML.jpg

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