Hennings G
Arzneimittelforschung. 1979;29(5):720-4.
The pharmacological actions of (+)-cyanidanol-3 [(+)-flavan-3,3',4',5,7-pentol, (+)-catechin, Catergen) in various experimental liver diseases are described according to the recent available literature. On this basis the hepatoprotective activity of the drug is due to its stabilizing effect on biological membranes and its specific inhibitory activity on the Fe-ADP-, CCl4- and CBrCl3- stimulated lipoperoxidation in vitro and in vivo.
根据最近可得的文献，描述了(+)-氰定醇-3[（+）-黄烷-3,3',4',5,7-戊醇、（+）-儿茶素、Catergen]在各种实验性肝脏疾病中的药理作用。在此基础上，该药物的肝脏保护活性归因于其对生物膜的稳定作用以及在体外和体内对Fe-ADP、CCl4和CBrCl3刺激的脂质过氧化的特异性抑制活性。
