Costa Davide, Ielapi Nicola, Bracale Umberto Marcello, Peluso Antonio, Minici Roberto, Andreucci Michele, Serra Raffaele
Department of Law, Economics and Sociology, University "Magna Graecia" of Catanzaro, 88100, Catanzaro, Italy.
Interuniversity Center of Phlebolymphology (CIFL), International Research and Educational Program in Clinical and Experimental Biotechnology. University "Magna Graecia" of Catanzaro, 88100, Catanzaro, Italy.
Heliyon. 2024 Apr 24;10(9):e30038. doi: 10.1016/j.heliyon.2024.e30038. eCollection 2024 May 15.
This study aimed to investigate the presence of sexual dysfunction (SD) in patients with Chronic Venous Disease (CVD) and if CVD treatments may have an impact on SD evolution in these patients.
Inclusion criteria were patients of both sexes and genders, with minimum age of 18, with first diagnosis of CVD. Exclusion criteria were presence of known sexual dysfunction of organic origin, arterial system diseases, malignancies and endocrine system diseases. Included patients were administered the ASEX (Arizona Sexual Experience) questionnaire that was administered at the moment of study inclusion (T0), and for patients that resulted affected from sexual dysfunction, were administered also, after CVD treatments at 6 months (T1) and after 12 months (T2).
A total of 649 patients with CVD were recruited. After the administration of the ASEX questionnaire, 122 patients (18.8 %) resulted affected from SD. Female sex, C3-C6 clinical stages, and the presence of Coronary Artery Disease (CAD), hypertension, and hyperlipidemia were more associated with the presence of SD. SD improved in all patients' population, especially after CVD treatment at T2.
CVD patients may experience SD, especially in female sex, in more advanced disease stages. SD in CVD patients appears to improve after adequate CVD treatment.
本研究旨在调查慢性静脉疾病（CVD）患者中性功能障碍（SD）的存在情况，以及CVD治疗是否可能对这些患者的SD演变产生影响。
纳入标准为年龄至少18岁、首次诊断为CVD的男女患者。排除标准为存在已知的器质性性功能障碍、动脉系统疾病、恶性肿瘤和内分泌系统疾病。纳入的患者在研究纳入时（T0）接受亚利桑那性体验（ASEX）问卷评估，对于患有性功能障碍的患者，在CVD治疗6个月后（T1）和12个月后（T2）也进行评估。
共招募了649例CVD患者。在进行ASEX问卷评估后，122例患者（18.8%）患有SD。女性、C3 - C6临床分期以及冠状动脉疾病（CAD）、高血压和高脂血症的存在与SD的发生更相关。所有患者群体的SD均有所改善，尤其是在T2期进行CVD治疗后。
CVD患者可能会出现SD，尤其是女性，在疾病更晚期时。CVD患者的SD在接受充分的CVD治疗后似乎有所改善。
