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FindMyApps 电子健康干预与常规数字护理的成本效益比较:一项随机对照试验的结果。

Cost-effectiveness of the FindMyApps eHealth intervention vs. digital care as usual: results from a randomised controlled trial.

机构信息

Department of Psychiatry, Amsterdam University Medical Centers, , Amsterdam, The Netherlands.

Department of Health Sciences, Vrije Universiteit Amsterdam, Amsterdam Public Health research institute, Amsterdam, The Netherlands.

出版信息

Aging Ment Health. 2024 Nov;28(11):1457-1470. doi: 10.1080/13607863.2024.2345128. Epub 2024 May 6.

Abstract

OBJECTIVES

Despite growing interest, the cost-effectiveness of eHealth interventions for supporting quality of life of people with dementia and their caregivers remains unclear. This study evaluated the cost-effectiveness of the FindMyApps intervention, compared to digital care-as-usual. FindMyApps aims to help people with dementia and their caregivers find and learn to use tablet apps that may support social participation and self-management of people with dementia and sense of competence of caregivers.

METHOD

A randomised controlled trial (Netherlands Trial Register NL8157) was conducted, including people with mild cognitive impairment (MCI) or mild dementia and their informal caregivers (FindMyApps  = 76, digital care-as-usual  = 74). Outcomes for people with MCI/dementia were Quality-Adjusted Life-Years (QALYs), calculated from EQ-5D-5L data and the Dutch tariff for utility scores, social participation (Maastricht Social Participation Profile) and quality of life (Adult Social Care Outcomes Toolkit), and for caregivers, QALYs and sense of competence (Short Sense of Competence Questionnaire). Societal costs were calculated using data collected with the RUD-lite instrument and the Dutch costing guideline. Multiple imputation was employed to fill in missing cost and effect data. Bootstrapped multilevel models were used to estimate incremental total societal costs and incremental effects between groups which were then used to calculate Incremental Cost-Effectiveness Ratios (ICERs). Cost-effectiveness acceptability curves were estimated.

RESULTS

In the FindMyApps group, caregiver SSCQ scores were significantly higher compared to care-as-usual = 150, mean difference = 0.75, 95% CI [0.14, 1.38]. Other outcomes did not significantly differ between groups. Total societal costs for people with dementia were not significantly different,  = 150, mean difference = €-774, 95%CI [-2.643, .,079]. Total societal costs for caregivers were significantly lower in the FindMyApps group compared to care-as-usual,  = 150, mean difference = € -392, 95% CI [-1.254, -26], largely due to lower supportive care costs, mean difference = €-252, 95% CI [-1.009, 42]. For all outcomes, the probability that FindMyApps was cost-effective at a willingness-to-pay threshold of €0 per point of improvement was 0.72 for people with dementia and 0.93 for caregivers.

CONCLUSION

FindMyApps is a cost-effective intervention for supporting caregivers' sense of competence. Further implementation of FindMyApps is warranted.

摘要

目的

尽管人们越来越关注,但电子健康干预措施对支持痴呆症患者及其照护者生活质量的成本效益仍不清楚。本研究评估了 FindMyApps 干预措施与数字常规护理相比的成本效益。FindMyApps 的目的是帮助痴呆症患者及其照护者找到并学习使用可能支持痴呆症患者社交参与和自我管理以及照护者能力感的平板电脑应用程序。

方法

进行了一项随机对照试验(荷兰试验登记处 NL8157),包括轻度认知障碍(MCI)或轻度痴呆症患者及其非专业照护者(FindMyApps 组=76 人,数字常规护理组=74 人)。MCI/痴呆症患者的结局指标为质量调整生命年(QALYs),由 EQ-5D-5L 数据和荷兰效用评分的收费标准计算得出,包括社交参与度(马斯特里赫特社会参与度量表)和生活质量(成人社会护理结局工具包),照护者的结局指标为 QALYs 和能力感(简短能力感问卷)。使用 RUD-lite 仪器和荷兰成本指南收集的数据计算社会成本。采用多重插补方法填补缺失的成本和效果数据。采用 bootstrap 多层模型估计组间增量总社会成本和增量效果,然后计算增量成本效益比(ICER)。估计成本效益可接受性曲线。

结果

在 FindMyApps 组中,与常规护理相比,照护者 SSCQ 评分显著升高(FindMyApps 组=150,平均差值=0.75,95%CI [0.14, 1.38])。其他结局指标在两组间无显著差异。痴呆症患者的总社会成本无显著差异(FindMyApps 组=150,平均差值=-774 欧元,95%CI [-2.643, 0.079])。与常规护理相比,FindMyApps 组的照护者总社会成本显著降低(FindMyApps 组=150,平均差值=-392 欧元,95%CI [-1.254, -26]),这主要归因于支持性护理费用降低,平均差值=-252 欧元,95%CI [-1.009, 42]。对于所有结局指标,FindMyApps 提高 1 分的意愿支付阈值为 0 欧元时,在照护者中具有成本效益的概率为 0.72,在痴呆症患者中为 0.93。

结论

FindMyApps 是一种支持照护者能力感的具有成本效益的干预措施。有必要进一步实施 FindMyApps。

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