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将FindMyApps与常规平板电脑使用进行比较,以促进轻度痴呆社区居民及其非正式照护者的社交健康:一项随机对照试验。

FindMyApps compared with usual tablet use to promote social health of community-dwelling people with mild dementia and their informal caregivers: a randomised controlled trial.

作者信息

Neal David P, Ettema Teake P, Zwan Marissa D, Dijkstra Karin, Finnema Evelyn, Graff Maud, Muller Majon, Dröes Rose-Marie

机构信息

Department of Psychiatry, Amsterdam UMC, Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands.

Amsterdam Public Health Research Institute, Mental Health Program, Amsterdam, the Netherlands.

出版信息

EClinicalMedicine. 2023 Aug 30;63:102169. doi: 10.1016/j.eclinm.2023.102169. eCollection 2023 Sep.

Abstract

BACKGROUND

FindMyApps is a tablet-based eHealth intervention designed to help people learn to use a tablet and find easy-to-use apps. This study evaluated the effectiveness of FindMyApps for supporting social health of people living with dementia, and sense of competence of their informal caregivers.

METHODS

A single-centre, two-arm, non-blinded randomised controlled trial was conducted (Netherlands Trial Register NL8157). From 1st January 2020 to 31st July 2022, community-dwelling people in the Netherlands with a pre-established diagnosis of mild cognitive impairment (MCI) or dementia (Brief Cognitive Rating Scale 17-32), an informal caregiver and internet connection were allocated by block randomisation to receive FindMyApps or digital care-as-usual. Primary outcomes (measured at baseline and after three months) for people with dementia/MCI were self-management (Adult Social Care Outcomes Toolkit total score) and social participation (Maastricht Social Participation Profile frequency and diversity scores), and for caregivers, sense of competence (Short Sense of Competence Questionnaire total score). Between-group differences were tested by MANCOVA or ANCOVA (alpha = 0.05).

FINDINGS

150 dyads were randomised (FindMyApps n = 76, care-as-usual n = 74). Follow-up data were available for 128 dyads (FindMyApps n = 64, care-as-usual n = 64), who were included in the analysis in the trial arm to which they were assigned. No harms of the intervention were identified. There were no statistically significant differences in outcomes for people with dementia/MCI at group level. Diagnosis and experiencing apathy appeared to be relevant effect modifiers of secondary outcomes (neuropsychiatric symptoms, positive affect, sense of belonging, and pleasurable activities). Caregivers who received FindMyApps had higher sense of competence at three months (F [1,123] = 7.01, p = 0.0092, η = 0.054).

INTERPRETATION

Overall we found no evidence that the FindMyApps intervention better supported social participation or self-management of people with MCI/dementia than digital care-as-usual. FindMyApps does seem to better support informal caregivers' sense of competence. For people with a diagnosis of mild dementia and older people, better tailored interventions, implementation and outcome measures may be needed.

FUNDING

Marie Skłodowska Curie Actions Innovative Training Network H2020 MSCA ITN, grant agreement number 813196.

摘要

背景

“找到我的应用程序”(FindMyApps)是一项基于平板电脑的电子健康干预措施,旨在帮助人们学习使用平板电脑并找到易于使用的应用程序。本研究评估了“找到我的应用程序”对支持痴呆症患者的社交健康及其非正式照护者的能力感的有效性。

方法

进行了一项单中心、双臂、非盲随机对照试验(荷兰试验注册编号NL8157)。从2020年1月1日至2022年7月31日,将荷兰已确诊为轻度认知障碍(MCI)或痴呆症(简易认知评定量表评分为17 - 32)、有一名非正式照护者且能联网的社区居民通过整群随机化分配,以接受“找到我的应用程序”或常规数字照护。痴呆症/MCI患者的主要结局指标(在基线和三个月后测量)为自我管理(成人社会照护结局工具包总分)和社会参与(马斯特里赫特社会参与概况频率和多样性得分),照护者的主要结局指标为能力感(简易能力感问卷总分)。组间差异通过多变量协方差分析或协方差分析进行检验(α = 0.05)。

研究结果

150对被试被随机分组(“找到我的应用程序”组n = 76,常规照护组n = 74)。128对被试有随访数据(“找到我的应用程序”组n = 64,常规照护组n = 64),这些被试被纳入其被分配的试验组进行分析。未发现该干预措施有不良影响。在组水平上,痴呆症/MCI患者的结局指标无统计学显著差异。诊断和冷漠似乎是次要结局指标(神经精神症状、积极情绪、归属感和愉悦活动)的相关效应修饰因素。接受“找到我的应用程序”干预的照护者在三个月时能力感更高(F [1,123] = 7.01,p = 0.0092,η = 0.054)。

解读

总体而言,我们没有发现证据表明“找到我的应用程序"干预措施比常规数字照护能更好地支持MCI/痴呆症患者的社会参与或自我管理。“找到我的应用程序”似乎确实能更好地支持非正式照护者的能力感。对于诊断为轻度痴呆症的患者和老年人,可能需要更有针对性的干预措施、实施方法和结局指标。

资金来源

玛丽·斯克沃多夫斯卡·居里行动创新培训网络H2020 MSCA ITN,资助协议编号813196。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28b7/10480525/0fb09854581b/gr1.jpg

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