Nutrient Metabolism and Signalling Laboratory, Department of Biochemistry and Molecular Biology, Metabolism, Diabetes and Obesity Program, Biomedicine Discovery Institute, Monash University, Melbourne, Australia.
Appetite and Behavioural Control Group, Department of Physiology, Metabolism, Diabetes and Obesity Program, Biomedicine Discovery Institute, Monash University, Melbourne, Australia.
J Exp Med. 2024 Jul 1;221(7). doi: 10.1084/jem.20240545. Epub 2024 May 6.
New studies (Tang et al. 2024. J. Exp. Med.https://doi.org/10.1084/jem.20231395) describe a liver stress pathway that is activated by certain chemotherapeutic drugs, which in turn induces a peptide hormone which partially mediates the lower food intake and body weight loss during chemotherapy treatment.
新的研究（Tang 等人，2024 年。《实验医学杂志》。https://doi.org/10.1084/jem.20231395）描述了一条肝脏应激通路，该通路被某些化疗药物激活，进而诱导产生一种肽激素，这种激素在一定程度上介导了化疗治疗期间的食物摄入减少和体重下降。
