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坏疽性脓皮病:一例凸显及时诊断重要性的病例

Pyoderma Gangrenosum: A Case Highlighting the Importance of Timely Diagnosis.

作者信息

Rukhshan Rabia, Eliogu Chioma, Mistry Anuja, Brar Simran, Mohd Arshad Ali, Ruck Lela

机构信息

Internal medicine, Texas Tech University Health Sciences Center El Paso Paul L. Foster School of Medicine, El Paso, USA.

Internal Medicine, Texas Tech University Health Sciences Center El Paso Paul L. Foster School of Medicine, El Paso, USA.

出版信息

Cureus. 2024 Apr 7;16(4):e57762. doi: 10.7759/cureus.57762. eCollection 2024 Apr.

Abstract

Pyoderma Gangrenosum (PG) is a distinctive dermatologic condition characterized by recurrent inflammatory ulcers, often manifesting with violaceous borders and undermined edges. We describe a 40-year-old male who presented with acute on chronic necrotic ulcer of the left index finger following foreign body penetration. Despite multiple emergency department visits and treatments for presumed recurrent cellulitis, including various debridements, his condition persisted without symptomatic relief. A high index of clinical suspicion, due to recurrent presentations and potential pathergy, prompted an excision biopsy which confirmed Pyoderma Gangrenosum (PG). Regrettably, due to delays in appropriate management, the patient chose amputation because of intolerable pain, highlighting the critical importance of timely diagnosis for optimal patient outcomes.

摘要

坏疽性脓皮病(PG)是一种独特的皮肤病,其特征为反复出现炎症性溃疡,通常表现为紫红色边界和潜行性边缘。我们描述了一名40岁男性,他因异物刺入后出现左示指慢性坏死性溃疡急性发作。尽管多次前往急诊科就诊并接受了针对疑似复发性蜂窝织炎的治疗,包括各种清创术,但其病情仍持续存在,症状未得到缓解。由于反复出现症状以及潜在的同形反应,高度的临床怀疑促使进行了切除活检,结果确诊为坏疽性脓皮病(PG)。遗憾的是,由于适当治疗的延误,患者因无法忍受的疼痛而选择了截肢,这凸显了及时诊断对于实现最佳患者预后的至关重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b32/11075739/47eb609036d0/cureus-0016-00000057762-i01.jpg

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