美法仑对人外周血T细胞的处理可促进体外B细胞产生免疫球蛋白。
Melphalan treatment of human peripheral T cells promotes Ig production by B cells in vitro.
作者信息
Baral E, Blomgren H, Wasserman J, von Stedingk L V, Rotstein S, Virving L
出版信息
Eur J Cancer Clin Oncol. 1985 Jan;21(1):81-4. doi: 10.1016/0277-5379(85)90204-4.
PMID:3871695
Abstract
Human blood B lymphocytes were cocultured with autologous T lymphocytes which were pretested with melphalan or adriamycin in the presence of pokeweed mitogen (PWM). Melphalan treatment of the cells produced an increased secretion of IgG and IgM, whereas adriamycin did not.
摘要
人血B淋巴细胞与经美法仑或阿霉素预处理的自体T淋巴细胞在商陆有丝分裂原（PWM）存在的情况下进行共培养。美法仑处理细胞后，IgG和IgM的分泌增加，而阿霉素处理则没有这种效果。
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