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一种将皮层反应与行为反应联系起来以研究视觉连续性错觉的多模态方法。

A multimodal approach connecting cortical and behavioural responses to the visual continuity illusion.

作者信息

Bailey Matthew C D, du Hoffmann Johann F, Dalley Jeffrey W

机构信息

Department of Psychology, University of Cambridge, Cambridge, UK.

Boehringer Ingelheim Pharma GmbH & Co, Biberach an der Riss, Germany.

出版信息

Brain Neurosci Adv. 2024 May 6;8:23982128241251685. doi: 10.1177/23982128241251685. eCollection 2024 Jan-Dec.

Abstract

In their recently published study, Gil, Valente and Shemesh combined behaviour, functional magnetic resonance imaging, electroencephalography and causal interventions to establish and validate a cortical processing substrate underlying the transition from static to dynamic visual states in the rat. Their research highlights the superior colliculus as the primary mediator of visual temporal discrimination by showing a direct correlation between behavioural and cortically derived flicker fusion frequency thresholds. This work provides the first empirical evidence addressing the previously established disparity between behavioural and cortically derived flicker fusion frequency thresholds. It demonstrates how important convergent multimodal approaches are to mapping and validating previously disputed cortical pathways. Here, we discuss and evaluate their work, suggesting possible future applications in the field of behavioural neuroscience.

摘要

在他们最近发表的研究中,吉尔、瓦伦特和谢梅什结合了行为学、功能磁共振成像、脑电图和因果干预,以建立并验证大鼠从静态视觉状态转变为动态视觉状态背后的皮质处理基质。他们的研究通过显示行为和皮质衍生的闪烁融合频率阈值之间的直接相关性,突出了上丘是视觉时间辨别力的主要调节者。这项工作提供了首个实证证据,解决了先前行为学和皮质衍生的闪烁融合频率阈值之间已确定的差异。它证明了收敛性多模态方法对于绘制和验证先前有争议的皮质通路有多重要。在此,我们讨论并评估他们的工作,提出行为神经科学领域可能的未来应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/031a/11077936/18328cb002e4/10.1177_23982128241251685-fig1.jpg

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