Key Laboratory of Micro-nano Electronic Devices and Smart Systems of Zhejiang Province, College of Information Science & Electronic Engineering, Zhejiang University, Hangzhou, 310027, China.
Key Laboratory of Biomedical Engineering of Education Ministry, Department of Biomedical Engineering, Zhejiang University, Hangzhou, 310027, China.
Sci Rep. 2017 Aug 10;7(1):7808. doi: 10.1038/s41598-017-07823-3.
In this paper, we present a portable wireless electrocorticography (ECoG) system. It uses a high resolution 32-channel flexible ECoG electrodes array to collect electrical signals of brain activities and to stimulate the lesions. Electronic circuits are designed for signal acquisition, processing and transmission using Bluetooth Low Energy 4 (LTE4) for wireless communication with cell phone. In-vivo experiments on a rat show that the flexible ECoG system can accurately record electrical signals of brain activities and transmit them to cell phone with a maximal sampling rate of 30 ksampling/s per channel. It demonstrates that the epilepsy lesions can be detected, located and treated through the ECoG system. The wireless ECoG system has low energy consumption and high brain spatial resolution, thus has great prospects for future application.
本文提出了一种便携式无线脑电描记术(ECoG)系统。它使用高分辨率的 32 通道柔性 ECoG 电极阵列来采集脑活动的电信号,并对病灶进行刺激。电子电路采用蓝牙低能 4(BLE4)进行信号采集、处理和传输,用于与手机进行无线通信。在大鼠体内实验中,该柔性 ECoG 系统可以准确地记录脑活动的电信号,并以最大 30 ksampling/s 每通道的采样率传输到手机上。实验表明,通过 ECoG 系统可以检测、定位和治疗癫痫病灶。该无线 ECoG 系统具有低能耗和高脑空间分辨率的特点,因此具有广阔的应用前景。