Riviati Nur, Indrajaya Taufik, Saleh Irsan, Ali Zulkhair, Indra Bima
University of Sriwijaya, Palembang, Indonesia.
Gerontol Geriatr Med. 2024 May 7;10:23337214241249914. doi: 10.1177/23337214241249914. eCollection 2024 Jan-Dec.
Serum albumin, known for its multifaceted role in health, is hypothesized to serve as a prognostic marker for older adults, both in hospital and community settings. Nine studies were included in the review, revealing consistent associations between low serum albumin levels and increased mortality risk in hospitalized older individuals. In community settings, low serum albumin levels were linked to higher mortality rates compared to those with normal levels. The synthesis of evidence underscores the potential of serum albumin as a prognostic marker for older adults, offering valuable insights for risk stratification and targeted interventions. While robust evidence supports its utility in hospital settings, further research is warranted in community settings to address current limitations and enhance the applicability of serum albumin as a prognostic tool. This review merges existing knowledge of the prognostic significance of serum albumin in older adults across hospital and community settings. The findings emphasize the importance of serum albumin as a potential prognostic marker, urging continued research efforts to refine its application in diverse healthcare contexts and improve outcomes for the aging population.
血清白蛋白在健康方面具有多方面作用,据推测它可作为老年人在医院和社区环境中的预后标志物。该综述纳入了9项研究,揭示了住院老年个体血清白蛋白水平低与死亡风险增加之间存在一致的关联。在社区环境中,与血清白蛋白水平正常的人相比,血清白蛋白水平低与更高的死亡率相关。证据的综合强调了血清白蛋白作为老年人预后标志物的潜力,为风险分层和靶向干预提供了有价值的见解。虽然有力的证据支持其在医院环境中的效用,但在社区环境中仍需进一步研究,以解决当前的局限性并提高血清白蛋白作为预后工具的适用性。本综述整合了血清白蛋白在医院和社区环境中对老年人预后意义的现有知识。研究结果强调了血清白蛋白作为潜在预后标志物的重要性,敦促继续开展研究工作,以完善其在不同医疗环境中的应用,并改善老年人群的预后。