急性前葡萄膜炎的季节性变化：HLA - B27阳性与HLA - B27阴性疾病之间的差异
Seasonal variation of acute anterior uveitis: differences between HLA-B27 positive and HLA-B27 negative disease.
作者信息
Ebringer R, White L, McCoy R, Tait B
出版信息
Br J Ophthalmol. 1985 Mar;69(3):202-4. doi: 10.1136/bjo.69.3.202.
Abstract
One hundred and seventy-five consecutive patients with acute anterior uveitis (AAU) were examined over a 24-month period. There was a significantly increased incidence of AAU during the months August to December (p less than 0.05). This increase was confined predominantly to the HLA-B27 negative group of patients (p less than 0.01). There was no significant monthly difference in incidence between males and females, between patients with first or recurrent attacks, or between patients with and without arthritis. These results suggest that seasonal environmental factors may play a role in the production of HLA-B27 negative AAU.
摘要
在24个月的时间里，对175例连续的急性前葡萄膜炎（AAU）患者进行了检查。8月至12月期间AAU的发病率显著增加（p<0.05）。这种增加主要局限于HLA - B27阴性患者组（p<0.01）。男性和女性之间、首次发作或复发患者之间、有关节炎和无关节炎患者之间的发病率每月均无显著差异。这些结果表明，季节性环境因素可能在HLA - B27阴性AAU的发生中起作用。
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