Palanisamy Jayasudha, Almutairi Mikhlid H, Almutairi Bader O
Department of Chemistry, Subramanya College of Arts and Science, Palani, Tamilnadu, 624618, India.
Department of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia.
J Fluoresc. 2025 May;35(5):3099-3108. doi: 10.1007/s10895-024-03744-3. Epub 2024 May 9.
A novel colorimetric and fluorogenic probe L based on hydrazine carbothioamide and 1,8-naphthalimide moieties has been designed and synthesized for the hypersensitive detection of Hg or Ag ions. The observed probe L showed colorimetric and fluorometric responses for these studies when Hg or Ag was added to the DMSO - HEPES buffer solution (pH = 7). An interference test with other metal ions was determined, and the high selectivity of Hg and Ag did not interfere with other metal ions in colorimetric and fluorogenic methods. The possible mechanism of binding of these metal ions and the probe L 1:1 complex was determined by H NMR. Additionally, the reversibility of the affinity of probe L with mercury (Hg and silver (Ag) ions was investigated by adding NaEDTA. The naked eye detected the "Off-On" type fluorescence sensor in the presence of Hg and EDTA. The tested test strip kits provided a strong probability of probe L with high response and rapid, sensitive detection with Hg ion, which may be suitable for practical use.
基于肼基硫代酰胺和1,8-萘二甲酰亚胺部分设计并合成了一种新型比色和荧光探针L，用于超灵敏检测汞或银离子。当向二甲基亚砜-HEPES缓冲溶液（pH = 7）中加入汞或银时，观察到的探针L对这些研究显示出比色和荧光响应。测定了与其他金属离子的干扰试验，汞和银的高选择性在比色和荧光方法中不干扰其他金属离子。通过核磁共振氢谱确定了这些金属离子与探针L 1:1配合物结合的可能机制。此外，通过加入乙二胺四乙酸二钠研究了探针L与汞（Hg）和银（Ag）离子亲和力的可逆性。在汞和乙二胺四乙酸存在下，肉眼检测到“开-关”型荧光传感器。测试的试纸试剂盒提供了探针L对汞离子具有高响应以及快速、灵敏检测的很大可能性，这可能适用于实际应用。
