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热觉传入通路中的感觉处理

Sensory processing in a thermal afferent pathway.

作者信息

Davies S N, Goldsmith G E, Hellon R F, Mitchell D

出版信息

J Neurophysiol. 1985 Feb;53(2):429-34. doi: 10.1152/jn.1985.53.2.429.

DOI:10.1152/jn.1985.53.2.429
PMID:3872350
Abstract

Extracellular recordings were made from cold-receptive afferent fibers in the trigeminal ganglion of rats anesthetized with halothane. By applying a standardized series of steady or changing temperatures to the receptive fields, we recorded the static and dynamic responses of the afferents. Comparable recordings were made from neurons in the marginal layer of the caudal trigeminal nucleus onto which the cold fibers synapse. The static and dynamic responses of the afferent fibers were reproduced faithfully by the second-order neurons, but at a much higher level of activity. Ganglionectomy silenced the second-order cells. Their continuous high level of activity appears to depend on the tonic input from the afferent fibers and not on any intrinsic circuits in the medulla.

摘要

在氟烷麻醉的大鼠三叉神经节中,对冷觉传入纤维进行细胞外记录。通过向感受野施加一系列标准化的稳定或变化温度,我们记录了传入纤维的静态和动态反应。对冷觉纤维突触连接的三叉神经尾侧核边缘层中的神经元进行了类似的记录。传入纤维的静态和动态反应被二级神经元忠实地再现,但活动水平要高得多。切除神经节后,二级细胞沉默。它们持续的高活动水平似乎依赖于传入纤维的紧张性输入,而不是延髓中的任何内在回路。

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引用本文的文献

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Effects of fluctuating skin temperature on thermoregulatory responses in man.皮肤温度波动对人体体温调节反应的影响。
J Physiol. 1986 Sep;378:241-52. doi: 10.1113/jphysiol.1986.sp016217.
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Are single-unit recordings useful in understanding thermoregulation?单神经元记录在理解体温调节方面有用吗?
Yale J Biol Med. 1986 Mar-Apr;59(2):197-203.
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Transmission of low temperature information in the rat trigeminal system.大鼠三叉神经系统中低温信息的传递
Pflugers Arch. 1985 May;404(1):86-7. doi: 10.1007/BF00581497.
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Sympathetic modulation of cold-receptive neurones in the trigeminal system of the rat.大鼠三叉神经系统中冷感受神经元的交感神经调制
J Physiol. 1985 Sep;366:315-29. doi: 10.1113/jphysiol.1985.sp015800.