Big Data Institute, Oxford University, Oxford, UK.
Department of Applied Mathematics and Theoretical Physics, University of Cambridge, Cambridge, UK.
Trans R Soc Trop Med Hyg. 2024 Sep 2;118(9):561-579. doi: 10.1093/trstmh/trae026.
To explore the effects of climate change on malaria and 20 neglected tropical diseases (NTDs), and potential effect amelioration through mitigation and adaptation, we searched for papers published from January 2010 to October 2023. We descriptively synthesised extracted data. We analysed numbers of papers meeting our inclusion criteria by country and national disease burden, healthcare access and quality index (HAQI), as well as by climate vulnerability score. From 42 693 retrieved records, 1543 full-text papers were assessed. Of 511 papers meeting the inclusion criteria, 185 studied malaria, 181 dengue and chikungunya and 53 leishmaniasis; other NTDs were relatively understudied. Mitigation was considered in 174 papers (34%) and adaption strategies in 24 (5%). Amplitude and direction of effects of climate change on malaria and NTDs are likely to vary by disease and location, be non-linear and evolve over time. Available analyses do not allow confident prediction of the overall global impact of climate change on these diseases. For dengue and chikungunya and the group of non-vector-borne NTDs, the literature privileged consideration of current low-burden countries with a high HAQI. No leishmaniasis papers considered outcomes in East Africa. Comprehensive, collaborative and standardised modelling efforts are needed to better understand how climate change will directly and indirectly affect malaria and NTDs.
为了探讨气候变化对疟疾和 20 种被忽视的热带病(NTDs)的影响,以及通过缓解和适应来减轻潜在影响,我们搜索了 2010 年 1 月至 2023 年 10 月期间发表的论文。我们对提取的数据进行了描述性综合。我们按国家和国家疾病负担、医疗保健可及性和质量指数(HAQI)以及气候脆弱性评分分析符合纳入标准的论文数量。在 42693 篇检索记录中,有 1543 篇全文论文进行了评估。在符合纳入标准的 511 篇论文中,185 篇研究了疟疾,181 篇研究了登革热和基孔肯雅热,53 篇研究了利什曼病;其他 NTDs 的研究相对较少。有 174 篇论文(34%)考虑了缓解措施,24 篇论文(5%)考虑了适应策略。气候变化对疟疾和 NTDs 的影响的幅度和方向可能因疾病和地点而异,是非线性的,并随时间演变。现有分析无法对气候变化对这些疾病的总体全球影响做出有信心的预测。对于登革热和基孔肯雅热以及非媒介传播 NTDs 组,文献更倾向于考虑 HAQI 较高的当前低负担国家。没有关于东非利什曼病的论文考虑到结果。需要进行全面、协作和标准化的建模工作,以更好地了解气候变化将如何直接和间接影响疟疾和 NTDs。