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里昂品系遗传性高血压大鼠脑细胞核内色氨酸羟化作用的体内速率

Rate of tryptophan hydroxylation in vivo in brain nuclei of genetically hypertensive rats of the Lyon strain.

作者信息

Denoroy L, Tappaz M L, Fety R, Vincent M, Renaud B, Sassard J

出版信息

Experientia. 1985 Apr 15;41(4):478-9. doi: 10.1007/BF01966156.

DOI:10.1007/BF01966156
PMID:3872808
Abstract

The rate of tryptophan hydroxylation in vivo is unaltered in brain areas of 5, 9 and 21 week-old Lyon genetically Hypertensive (LH) rats as compared to both Lyon Normotensive (LN) and Low Blood Pressure (LL) rats, except for a decrease in the C1 area of the medulla oblongata in 9 week-old animals.

摘要

与里昂正常血压（LN）大鼠和低血压（LL）大鼠相比，5周龄、9周龄和21周龄的里昂遗传性高血压（LH）大鼠脑区中色氨酸羟化速率未发生改变，但9周龄动物的延髓C1区有所下降。

相似文献

1
Rate of tryptophan hydroxylation in vivo in brain nuclei of genetically hypertensive rats of the Lyon strain.里昂品系遗传性高血压大鼠脑细胞核内色氨酸羟化作用的体内速率
Experientia. 1985 Apr 15;41(4):478-9. doi: 10.1007/BF01966156.
2
A microassay for simultaneous measurement of in vivo rates of tryptophan hydroxylation and levels of serotonin in discrete brain nuclei.一种用于同时测量离散脑核中色氨酸羟化的体内速率和血清素水平的微量测定法。
J Neurosci Methods. 1982 Jul;6(1-2):45-58. doi: 10.1016/0165-0270(82)90015-2.
3
Selective reduction of adrenaline turnover in the dorsal midline area of the caudal medulla oblongata and increase of hypothalamic adrenaline levels in the Lyon strain of genetically hypertensive rats.遗传性高血压大鼠里昂品系中，延髓尾端背中线区域肾上腺素周转的选择性降低及下丘脑肾上腺素水平的升高。
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Serotonin turnover in discrete hypothalamic nuclei and mesencephalic raphe nuclei of young and adult spontaneously hypertensive rats.年轻和成年自发性高血压大鼠下丘脑离散核团及中脑缝际核团中的5-羟色胺周转率
Brain Res. 1986 Aug 6;379(2):257-63. doi: 10.1016/0006-8993(86)90779-1.
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In vivo tryptophan hydroxylase activity in rat major cerebral arteries is decreased by dorsal raphe nucleus lesions.
J Neurochem. 1996 Nov;67(5):2060-5. doi: 10.1046/j.1471-4159.1996.67052060.x.
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Age related changes in the effect of electroconvulsive shock (ECS) on the in vivo hydroxylation of tyrosine and tryptophan in rat brain.电休克（ECS）对大鼠脑内酪氨酸和色氨酸体内羟化作用的影响随年龄的变化
Brain Res. 1977 Aug 12;131(2):313-20. doi: 10.1016/0006-8993(77)90523-6.
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Daily variations in in vivo tryptophan hydroxylation and in the contents of serotonin and 5-hydroxyindoleacetic acid in discrete brain areas of the rat.大鼠离散脑区中色氨酸羟化作用以及血清素和5-羟吲哚乙酸含量的每日变化。
J Neural Transm Gen Sect. 1993;92(2-3):137-50. doi: 10.1007/BF01244873.
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Effect of hypercapnia and hypocapnia on tryptophan and tyrosine hydroxylation in rat brain.高碳酸血症和低碳酸血症对大鼠脑内色氨酸和酪氨酸羟化的影响。
Acta Physiol Scand. 1977 Apr;99(4):503-9. doi: 10.1111/j.1748-1716.1977.tb10404.x.
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In vivo rate of serotonin synthesis in brain and spinal cord of young, spontaneously hypertensive rats.年轻自发性高血压大鼠脑和脊髓中5-羟色胺合成的体内速率
Eur J Pharmacol. 1979 Jan 15;53(3):301-5. doi: 10.1016/0014-2999(79)90137-7.
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NE turnover in genetically hypertensive rats of Lyon strain. I. Brain nuclei.里昂品系遗传性高血压大鼠的去甲肾上腺素代谢。I. 脑核团
Am J Physiol. 1988 Oct;255(4 Pt 2):H729-35. doi: 10.1152/ajpheart.1988.255.4.H729.

本文引用的文献

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Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
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Review of the role of the central serotonergic neuronal system in blood pressure regulation.中枢5-羟色胺能神经元系统在血压调节中的作用综述。
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4
Estimation of the rate of tryptophan hydroxylation in vivo: a sensitive microassay in discrete rat brain nuclei.体内色氨酸羟化速率的测定：一种用于离散大鼠脑细胞核的灵敏微量测定法。
J Neurochem. 1980 Apr;34(4):933-40. doi: 10.1111/j.1471-4159.1980.tb09668.x.
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Isolated removal of hypothalamic or other brain nuclei of the rat.大鼠下丘脑或其他脑核的单独切除。
Brain Res. 1973 Sep 14;59:449-50. doi: 10.1016/0006-8993(73)90290-4.
6
Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in vivo using an inhibitor of the aromatic amino acid decarboxylase.使用芳香族氨基酸脱羧酶抑制剂在体内同时测量大脑中酪氨酸羟化酶和色氨酸羟化酶的活性。
Naunyn Schmiedebergs Arch Pharmacol. 1972;275(2):153-68. doi: 10.1007/BF00508904.
7
Tryptophan hydroxylase: activation in vivo following stimulation of central serotonergic neurons.色氨酸羟化酶：中枢5-羟色胺能神经元受刺激后在体内的激活
Biochem Pharmacol. 1975 Nov 1;24(21):2019-23. doi: 10.1016/0006-2952(75)90397-4.
8
In vivo rate of serotonin synthesis in brain and spinal cord of young, spontaneously hypertensive rats.年轻自发性高血压大鼠脑和脊髓中5-羟色胺合成的体内速率
Eur J Pharmacol. 1979 Jan 15;53(3):301-5. doi: 10.1016/0014-2999(79)90137-7.