Maj Institute of Pharmacology, Polish Academy of Sciences, Smętna Street 12, 31-343 Kraków, Poland.
Molecules. 2024 Apr 27;29(9):2014. doi: 10.3390/molecules29092014.
Polyphenols are ubiquitous plant metabolites that demonstrate biological activities essential to plant-environment interactions. They are of interest to plant food consumers, as well as to the food, pharmaceutical and cosmetic industry. The class of the plant metabolites comprises both widespread (chlorogenic acids, luteolin, quercetin) and unique compounds of diverse chemical structures but of the common biosynthetic origin. Polyphenols next to sesquiterpenoids are regarded as the major class of the Inuleae-Inulinae metabolites responsible for the pharmacological activity of medicinal plants from the subtribe ( spp., spp., spp., spp. and others). Recent decades have brought a rapid development of molecular and analytical techniques which resulted in better understanding of the taxonomic relationships within the Inuleae tribe and in a plethora of data concerning the chemical constituents of the Inuleae-Inulinae. The current taxonomical classification has introduced changes in the well-established botanical names and rearranged the genera based on molecular plant genetic studies. The newly created chemical data together with the earlier phytochemical studies may provide some complementary information on biochemical relationships within the subtribe. Moreover, they may at least partly explain pharmacological activities of the plant preparations traditionally used in therapy. The current review aimed to systematize the knowledge on the polyphenols of the Inulae-Inulinae.
多酚是普遍存在于植物中的代谢产物，具有与植物-环境相互作用相关的重要生物活性。它们不仅是植物性食物消费者感兴趣的对象，也受到食品、制药和化妆品行业的关注。植物代谢产物的类别包括广泛存在的（绿原酸、木樨草素、槲皮素）和具有不同化学结构但具有共同生物合成来源的独特化合物。多酚类化合物与倍半萜类化合物一起被认为是负责亚科（ spp.、 spp.、 spp.、 spp. 和其他）药用植物药理活性的主要代谢产物类群。近几十年来，分子和分析技术的快速发展使人们更好地理解了菊科植物族内的分类关系，并提供了大量关于菊科-旋覆花族化学成分的数据。当前的分类学分类对已确立的植物学名称进行了修改，并根据分子植物遗传学研究重新排列了属。新创建的化学数据与早期的植物化学研究相结合，可以为亚科内的生化关系提供一些补充信息。此外，它们至少可以部分解释传统上用于治疗的植物制剂的药理活性。本综述旨在系统地总结菊科-旋覆花族多酚的知识。
