School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW 2308, Australia.
Immune Health Research Program, Hunter Medical Research Institute, Newcastle, NSW 2305, Australia.
Nutrients. 2024 May 2;16(9):1380. doi: 10.3390/nu16091380.
Community screening for sarcopenia is complex, with barriers including access to specialized equipment and trained staff to conduct body composition, strength and function assessment. In the current study, self-reported dietary protein intake and physical activity (PA) in adults ≥65 years was assessed relative to sarcopenia risk, as determined by body composition, strength and physical function assessments, consistent with the European Working Group on Sarcopenia in Older People (EWGSOP) definition. Of those screened ( = 632), 92 participants (77% female) were assessed as being at high risk of developing sarcopenia on the basis of dietary protein intake ≤1 g∙kg∙day [0.9 (0.7-0.9) g∙kg∙day] and moderate intensity physical activity <150 min.week. A further 31 participants (65% female) were defined as being at low risk, with both protein intake [1.2 (1.1-1.5) g∙kg∙day] and PA greater than the cut-off values. High-risk participants had reduced % lean mass [53.5 (7.8)% versus 54.8 (6.1)%, 0.001] and impaired strength and physical function. Notably, high-risk females exhibited greater deficits in lean mass and strength, with minimal differences between groups for males. In community-dwelling older adults, self-reported low protein intake and low weekly PA is associated with heightened risk for sarcopenia, particularly in older women. Future research should determine whether early intervention in older adults with low protein intake and PA attenuates functional decline.
社区肌少症筛查较为复杂,存在诸多障碍,包括缺乏专门设备以及缺乏进行身体成分、力量和功能评估的训练有素的人员。在本研究中,根据身体成分、力量和身体功能评估,评估了≥65 岁成年人的自我报告的膳食蛋白质摄入和体力活动(PA)与肌少症风险的相关性,这与欧洲老年人肌少症工作组(EWGSOP)的定义一致。在所筛查的人群中(n = 632),有 92 名参与者(77%为女性)根据膳食蛋白质摄入≤1 g·kg·day[0.9(0.7-0.9)g·kg·day]和中强度 PA<150 min·week 被评估为有发生肌少症的高风险。另有 31 名参与者(65%为女性)被定义为低风险,他们的蛋白质摄入[1.2(1.1-1.5)g·kg·day]和 PA 均高于截止值。高风险组参与者的瘦体重百分比[53.5(7.8)%与 54.8(6.1)%,0.001]降低,力量和身体功能受损。值得注意的是,高风险女性的瘦体重和力量下降更为明显,而男性组之间的差异最小。在社区居住的老年人中,自我报告的低蛋白质摄入和低每周 PA 与肌少症风险增加相关,尤其是在老年女性中。未来的研究应确定在蛋白质摄入和 PA 较低的老年人中早期干预是否可以减轻功能下降。