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聚合物辅助层层组装可穿戴传感器在健康监测中的进展。

Advancements in Polymer-Assisted Layer-by-Layer Fabrication of Wearable Sensors for Health Monitoring.

机构信息

College of Materials and Environmental Engineering, Hangzhou Dianzi University, Hangzhou 310018, China.

Qianwan Institute, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China.

出版信息

Sensors (Basel). 2024 May 1;24(9):2903. doi: 10.3390/s24092903.

Abstract

Recent advancements in polymer-assisted layer-by-layer (LbL) fabrication have revolutionized the development of wearable sensors for health monitoring. LbL self-assembly has emerged as a powerful and versatile technique for creating conformal, flexible, and multi-functional films on various substrates, making it particularly suitable for fabricating wearable sensors. The incorporation of polymers, both natural and synthetic, has played a crucial role in enhancing the performance, stability, and biocompatibility of these sensors. This review provides a comprehensive overview of the principles of LbL self-assembly, the role of polymers in sensor fabrication, and the various types of LbL-fabricated wearable sensors for physical, chemical, and biological sensing. The applications of these sensors in continuous health monitoring, disease diagnosis, and management are discussed in detail, highlighting their potential to revolutionize personalized healthcare. Despite significant progress, challenges related to long-term stability, biocompatibility, data acquisition, and large-scale manufacturing are still to be addressed, providing insights into future research directions. With continued advancements in polymer-assisted LbL fabrication and related fields, wearable sensors are poised to improve the quality of life for individuals worldwide.

摘要

聚合物辅助逐层(LbL)制造的最新进展彻底改变了用于健康监测的可穿戴传感器的发展。LbL 自组装作为一种在各种基底上制造保形、灵活和多功能薄膜的强大而通用的技术已经出现,使其特别适合制造可穿戴传感器。天然和合成聚合物的掺入在提高这些传感器的性能、稳定性和生物相容性方面发挥了关键作用。本文综述了 LbL 自组装的原理、聚合物在传感器制造中的作用以及用于物理、化学和生物传感的各种 LbL 制造的可穿戴传感器。详细讨论了这些传感器在连续健康监测、疾病诊断和管理中的应用,强调了它们在个性化医疗方面的潜力。尽管取得了重大进展,但与长期稳定性、生物相容性、数据采集和大规模制造相关的挑战仍有待解决,为未来的研究方向提供了思路。随着聚合物辅助 LbL 制造和相关领域的不断进步,可穿戴传感器有望提高全球个人的生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a3f/11086243/106d9692272d/sensors-24-02903-g001.jpg

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