Zhejiang Key Laboratory of Horticultural Crop Quality Improvement, Zhejiang University, Hangzhou 310058, China.
Department of Chemistry, Zhejiang University, Hangzhou 310058, China.
Food Chem. 2024 Sep 1;451:139408. doi: 10.1016/j.foodchem.2024.139408. Epub 2024 Apr 23.
Fruits are a rich source of polysaccharides, and an increasing number of studies have shown that polysaccharides from fruits have a wide range of biological functions. Here, we thoroughly review recent advances in the study of the bioactivities, structures, and structure-activity relationships of fruit polysaccharides, especially highlighting the structure-activity influencing factors such as extraction methods and chemical modifications. Different extraction methods cause differences in the primary structures of polysaccharides, which in turn lead to different polysaccharide biological activities. Differences in the degree of modification, molecular weight, substitution position, and chain conformation caused by chemical modification can all affect the biological activities of fruit polysaccharides. Furthermore, we summarize the applications of fruit polysaccharides in the fields of pharmacy and medicine, foods, cosmetics, and materials. The challenges and perspectives for fruit polysaccharide research are also discussed.
水果是多糖的丰富来源，越来越多的研究表明，水果多糖具有广泛的生物功能。在这里，我们全面回顾了水果多糖生物活性、结构和构效关系研究的最新进展，特别强调了提取方法和化学修饰等结构-活性影响因素。不同的提取方法导致多糖的一级结构存在差异，进而导致多糖的生物活性不同。化学修饰引起的修饰程度、分子量、取代位置和链构象的差异都会影响水果多糖的生物活性。此外，我们总结了水果多糖在药学和医学、食品、化妆品和材料等领域的应用。还讨论了水果多糖研究面临的挑战和展望。
