Meneghini C L, Bonifazi E
Acta Derm Venereol Suppl (Stockh). 1985;114:140-2. doi: 10.2340/00015555114140142.
Many immunological alterations have been reported in atopic dermatitis, and it is likely that in some cases they are capable of worsening the clinical course of atopic dermatitis (AD). More frequently these alterations are responsible for conditions associated with AD such as asthma, food allergy and infections. It seems probable that in some cases they are evidence of a preclinical allergic manifestation. However, in most cases, it is likely that the immunological alterations do not affect significantly the clinical course of the disease.
许多免疫改变已在特应性皮炎中被报道，并且在某些情况下，它们很可能会使特应性皮炎（AD）的临床病程恶化。这些改变更常见地是导致与AD相关的病症，如哮喘、食物过敏和感染。在某些情况下，它们似乎可能是临床前过敏表现的证据。然而，在大多数情况下，免疫改变可能不会显著影响该疾病的临床病程。
