Molecular Medicine Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Nephrology and Urology Research Center, Clinical Sciences Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
BMC Infect Dis. 2024 May 13;24(1):488. doi: 10.1186/s12879-024-09279-z.
Prioritizing prevention over treatment has been a longstanding principle in the world health system. This study aims to compare the demographic changes, mortality, clinical, and paraclinical findings of patients hospitalized in the Corona ward before and after the start of general vaccination.
This cross-sectional study utilized the simple random sampling method in 2022, analyzing 300 medical records of patients admitted to the Corona ward at 22 Bahman Khaf Hospital. Data were collected using a checklist with the help of the Medical Care Monitoring System and analyzed using SPSS-22 statistical software and Chi-square statistical test at a significance level of p < 0.05.
Before the start of general vaccination for COVID-19, the majority of patients were hospitalized in the Corona Intensive Care Unit (59.3%), aged between 51 and 65 years (47.3%), hospitalized for more than 3 days (54%), required intubation (49.3%), had SPO2 < 93% (60.7%), and exhibited common symptoms such as cough, shortness of breath, and loss of consciousness. Paraclinical findings included positive CRP, decreased lymphocytes, and ground glass opacity (GGO). After the start of general vaccination for COVID-19, most patients were hospitalized in the general care department of Corona (68%), aged between 36 and 50 years (47.3%), hospitalized for less than three days (66%), required intubation (20%), had SPO2 ≥ 93% (77.3%), and exhibited common symptoms such as weakness, headache, and body pain. Paraclinical findings were within the normal range.
General vaccination for COVID-19 has significantly reduced patient mortality and morbidity. Health policymakers should prioritize general vaccination to achieve herd immunity and improve public health.
在世界卫生体系中，优先预防而非治疗一直是一个长期存在的原则。本研究旨在比较接种普通疫苗前后在 Corona 病房住院的患者的人口统计学变化、死亡率、临床和辅助检查结果。
这是一项 2022 年的横断面研究，采用简单随机抽样方法，分析了 22 巴曼·哈夫医院 Corona 病房的 300 名患者的病历。使用检查表收集数据，借助医疗保健监测系统，采用 SPSS-22 统计软件进行分析，采用卡方检验，显著水平为 p<0.05。
在开始普遍接种 COVID-19 疫苗之前，大多数患者住院于 Corona 重症监护病房（59.3%），年龄在 51-65 岁之间（47.3%），住院时间超过 3 天（54%），需要插管（49.3%），SPO2<93%（60.7%），表现出咳嗽、呼吸急促和意识丧失等常见症状。辅助检查结果包括 CRP 阳性、淋巴细胞减少和磨玻璃样混浊（GGO）。在开始普遍接种 COVID-19 疫苗之后，大多数患者住院于 Corona 普通病房（68%），年龄在 36-50 岁之间（47.3%），住院时间少于 3 天（66%），需要插管（20%），SPO2≥93%（77.3%），表现出乏力、头痛和身体疼痛等常见症状。辅助检查结果在正常范围内。
COVID-19 的普遍接种显著降低了患者的死亡率和发病率。卫生政策制定者应优先考虑普遍接种，以实现群体免疫，改善公共卫生。
