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本文引用的文献

1
Intramedullary Spinal Cord Abscess with Concomitant Spinal Degenerative Diseases: A Case Report and Systematic Literature Review.伴有脊髓退行性疾病的髓内脊髓脓肿:一例报告及系统文献综述
J Clin Med. 2022 Aug 31;11(17):5148. doi: 10.3390/jcm11175148.
2
Streptococcus pneumoniae meningitis complicated by an intramedullary abscess: a case report and review of the literature.肺炎链球菌脑膜炎并发髓内脓肿:一例报告并文献复习
J Med Case Rep. 2016 Oct 19;10(1):290. doi: 10.1186/s13256-016-1080-7.
3
Intramedullary spinal cord abscess associated with spinal dural arteriovenous fistula.与脊髓硬脊膜动静脉瘘相关的脊髓髓内脓肿。
J Neurol Sci. 2016 Sep 15;368:94-6. doi: 10.1016/j.jns.2016.06.068. Epub 2016 Jul 1.
4
Intramedullary spinal cord abscess and subsequent granuloma formation: a rare complication of vertebral osteomyelitis detected by diffusion-weighted magnetic resonance imaging.脊髓髓内脓肿及随后的肉芽肿形成:一种通过扩散加权磁共振成像检测到的椎体骨髓炎罕见并发症。
Neurosurg Focus. 2014 Aug;37(2):E12. doi: 10.3171/2014.6.FOCUS14141.
5
Intramedullary cervical abscess in the setting of aortic valve endocarditis.主动脉瓣心内膜炎并发颈髓内脓肿。
Asian Cardiovasc Thorac Ann. 2015 Jan;23(1):64-6. doi: 10.1177/0218492313495861. Epub 2013 Oct 17.
6
Metachronous occurrence of an intramedullary abscess following radical excision of a cervical intramedullary pilocytic astrocytoma.宫颈髓内毛细胞型星形细胞瘤根治性切除术后髓内脓肿的异时发生。
Neurol India. 2013 May-Jun;61(3):322-4. doi: 10.4103/0028-3886.115089.
7
Intramedullary spinal cord abscess as complication of lumbar puncture: a case-based update.脊髓内脓肿作为腰椎穿刺的并发症:基于病例的最新进展
Childs Nerv Syst. 2013 Jul;29(7):1061-8. doi: 10.1007/s00381-013-2093-9. Epub 2013 Apr 5.
8
Intrathecal granuloma and intramedullary abscess associated with an intrathecal morphine pump.鞘内肉芽肿和鞘内脓肿与鞘内吗啡泵相关。
Neuromodulation. 2007 Jan;10(1):6-11. doi: 10.1111/j.1525-1403.2007.00081.x.
9
Intramedullary spinal cord abscess treated with antibiotic therapy--case report and review.抗生素治疗脊髓髓内脓肿——病例报告及文献复习
Neurol Med Chir (Tokyo). 2009 Jun;49(6):262-8. doi: 10.2176/nmc.49.262.
10
Intramedullary abscess of the spinal cord.脊髓髓内脓肿
Lancet. 1949 Jul 30;2(6570):193-5. doi: 10.1016/s0140-6736(49)91194-0.

脊髓髓内脓肿作为术后并发症:一例报告。

Intramedullary spinal cord abscess as postoperative complication: A case report.

作者信息

Valeri Amber Lynn, Alayli Adam, Gordon Jonah, Lockard Gavin, Tran Nam D

机构信息

Department of Neurosurgery, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, United States.

Morsani College of Medicine, Tampa, FL, United States.

出版信息

Surg Neurol Int. 2024 May 3;15:147. doi: 10.25259/SNI_176_2023. eCollection 2024.

DOI:10.25259/SNI_176_2023
PMID:38741995
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11090602/
Abstract

BACKGROUND

Intramedullary spinal cord abscesses (ISCA) can result in high morbidity and mortality if not treated in a timely manner. The incidence and outcomes of postsurgical ISCA are unknown. We present a case of a 52-year-old male patient with neurofibromatosis type 1 who developed an intramedullary spinal cord abscess after a previous resection of a cervical intradural, extramedullary neurofibroma.

CASE DESCRIPTION

A 52-year-old male with a history of neurofibromatosis type 1 had previously undergone multiple resections of cervical intradural, extramedullary neurofibromas with internal stabilization. Sixteen months after his initial surgery, he developed acute-onset interscapular pain with bilateral lower extremity pain and left hemi-body weakness. Magnetic resonance imaging (MRI) of the cervical spine demonstrated an enlarging contrast-enhancing intramedullary lesion. Surgical exploration and evacuation of the lesion were completed. Intramedullary cultures confirmed a abscess. After abscess evacuation and intravenous antibiotics, the patient's symptoms resolved.

CONCLUSION

Given the potential for permanent neurologic damage and loss of independence with intramedullary spinal cord abscess, we advocate that clinicians maintain a high index of suspicion in the postsurgical patient. Diagnostic imaging through contrasted MRI or computed tomography myelogram should be obtained, and prompt intervention, including evacuation and/or antibiotics, should be implemented for the best chance of a favorable outcome.

摘要

背景

脊髓髓内脓肿(ISCA)若不及时治疗可导致高发病率和死亡率。术后ISCA的发病率及预后尚不清楚。我们报告一例52岁1型神经纤维瘤病男性患者,其在先前切除颈椎硬膜内、髓外神经纤维瘤后发生了脊髓髓内脓肿。

病例描述

一名有1型神经纤维瘤病病史的52岁男性患者,此前曾多次接受颈椎硬膜内、髓外神经纤维瘤切除术并进行内固定。初次手术后16个月,他出现急性发作的肩胛间疼痛,伴有双侧下肢疼痛和左侧半身无力。颈椎磁共振成像(MRI)显示髓内病变增大且有强化。完成了病变的手术探查和清除。髓内培养证实为脓肿。脓肿清除并静脉应用抗生素后,患者症状缓解。

结论

鉴于脊髓髓内脓肿有导致永久性神经损伤和丧失独立生活能力的可能性,我们主张临床医生对术后患者保持高度警惕。应通过增强MRI或计算机断层扫描脊髓造影进行诊断性成像,并应立即进行干预,包括脓肿清除和/或应用抗生素,以获得最佳的良好预后机会。