Valeri Amber Lynn, Alayli Adam, Gordon Jonah, Lockard Gavin, Tran Nam D
Department of Neurosurgery, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, United States.
Morsani College of Medicine, Tampa, FL, United States.
Surg Neurol Int. 2024 May 3;15:147. doi: 10.25259/SNI_176_2023. eCollection 2024.
Intramedullary spinal cord abscesses (ISCA) can result in high morbidity and mortality if not treated in a timely manner. The incidence and outcomes of postsurgical ISCA are unknown. We present a case of a 52-year-old male patient with neurofibromatosis type 1 who developed an intramedullary spinal cord abscess after a previous resection of a cervical intradural, extramedullary neurofibroma.
A 52-year-old male with a history of neurofibromatosis type 1 had previously undergone multiple resections of cervical intradural, extramedullary neurofibromas with internal stabilization. Sixteen months after his initial surgery, he developed acute-onset interscapular pain with bilateral lower extremity pain and left hemi-body weakness. Magnetic resonance imaging (MRI) of the cervical spine demonstrated an enlarging contrast-enhancing intramedullary lesion. Surgical exploration and evacuation of the lesion were completed. Intramedullary cultures confirmed a abscess. After abscess evacuation and intravenous antibiotics, the patient's symptoms resolved.
Given the potential for permanent neurologic damage and loss of independence with intramedullary spinal cord abscess, we advocate that clinicians maintain a high index of suspicion in the postsurgical patient. Diagnostic imaging through contrasted MRI or computed tomography myelogram should be obtained, and prompt intervention, including evacuation and/or antibiotics, should be implemented for the best chance of a favorable outcome.
脊髓髓内脓肿(ISCA)若不及时治疗可导致高发病率和死亡率。术后ISCA的发病率及预后尚不清楚。我们报告一例52岁1型神经纤维瘤病男性患者,其在先前切除颈椎硬膜内、髓外神经纤维瘤后发生了脊髓髓内脓肿。
一名有1型神经纤维瘤病病史的52岁男性患者,此前曾多次接受颈椎硬膜内、髓外神经纤维瘤切除术并进行内固定。初次手术后16个月,他出现急性发作的肩胛间疼痛,伴有双侧下肢疼痛和左侧半身无力。颈椎磁共振成像(MRI)显示髓内病变增大且有强化。完成了病变的手术探查和清除。髓内培养证实为脓肿。脓肿清除并静脉应用抗生素后,患者症状缓解。
鉴于脊髓髓内脓肿有导致永久性神经损伤和丧失独立生活能力的可能性,我们主张临床医生对术后患者保持高度警惕。应通过增强MRI或计算机断层扫描脊髓造影进行诊断性成像,并应立即进行干预,包括脓肿清除和/或应用抗生素,以获得最佳的良好预后机会。