Ehara Takuro, Suzuki Tomonari, Mizuno Reina, Shirahata Mitsuaki, Mishima Kazuhiko, Homma Taku
Department of Neuro-Oncology/Neurosurgery, International Medical Center, Saitama Medical University, Hidaka, Saitama, Japan.
Department of Pathology, International Medical Center, Saitama Medical University, Hidaka, Saitama, Japan.
NMC Case Rep J. 2024 Feb 14;11:43-47. doi: 10.2176/jns-nmc.2023-0144. eCollection 2024.
Intramedullary spinal cord abscess is a rare and severe infectious disease characterized by devastating neurological deficits. We report a case of cervical intramedullary spinal cord abscess in a 74-year-old diabetic male with a 3-day history of neck pain and weakness in the right lower extremity. Magnetic resonance imaging revealed a ring-shaped contrast lesion in C3-C6 of the cervical spinal cord with extensive edema. Further, 1 day after admission, he became comatose (Glasgow Coma Scale E1VtM1), and a computed tomography head scan revealed hydrocephalus. Despite emergency ventricular drainage, the patient's level of consciousness remained unchanged. Magnetic resonance imaging performed 1 day after surgery revealed bilateral intracranial extension of the abscess into the thalamus and caudate nucleus. The patient died 19 days after admission. Our report is the first case of extensive brain abscess development over a short period. Based on our experience, prompt administration of antibiotics and emergency abscess drainage of the cervical cord (and ventricular drainage, if necessary) are recommended in cases of neurological deterioration in patients with cervical intramedullary spinal cord abscess.
脊髓髓内脓肿是一种罕见且严重的感染性疾病,其特征为严重的神经功能缺损。我们报告一例74岁糖尿病男性的颈段脊髓髓内脓肿病例,该患者有3天颈部疼痛及右下肢无力病史。磁共振成像显示颈髓C3 - C6节段有环形强化病灶并伴有广泛水肿。此外,入院1天后,患者昏迷(格拉斯哥昏迷量表评分为E1VtM1),头颅计算机断层扫描显示脑积水。尽管进行了紧急脑室引流,但患者意识水平仍未改变。术后1天的磁共振成像显示脓肿双侧颅内蔓延至丘脑和尾状核。患者入院19天后死亡。我们的报告是首例短期内广泛脑脓肿形成的病例。根据我们的经验,对于颈段脊髓髓内脓肿患者出现神经功能恶化的情况,建议及时使用抗生素并紧急进行颈髓脓肿引流(必要时进行脑室引流)。