在国际评估艾滋病联合会的艾滋病流行病学数据库中，有艾滋病毒暴露史的非洲婴儿中未经确认的艾滋病毒聚合酶链反应检测结果呈阳性的比例很高。
High Prevalence of Unconfirmed Positive HIV Polymerase Chain Reaction Test Results Among African Infants With HIV Exposure in the International Epidemiology Databases to Evaluate AIDS Consortium.
作者信息
Carlucci James G, Huntington Thomas, Technau Karl-Günter, Yotebieng Marcel, Leroy Valériane, Anderson Kim, Amorissani-Folquet Madeleine, Wools-Kaloustian Kara, Edmonds Andrew
机构信息
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Indiana University School of Medicine, Indianapolis, Indiana, USA.
出版信息
Clin Infect Dis. 2024 Dec 17;79(6):1475-1478. doi: 10.1093/cid/ciae251.
Abstract
In a large, multiregional cohort of African infants with human immunodeficiency virus (HIV) exposure, 44% of those with a positive HIV polymerase chain reaction test lacked a confirmatory positive test. Efforts are needed to ensure high-fidelity implementation of HIV testing algorithms so that all positive results are confirmed.
摘要
在一个涉及大量非洲地区、暴露于人类免疫缺陷病毒（HIV）的婴儿队列中，HIV聚合酶链反应检测呈阳性的婴儿中有44%缺乏确诊阳性检测结果。需要做出努力以确保HIV检测算法的高保真实施，从而使所有阳性结果都能得到确认。
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