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改善学龄儿童的酒精和物质使用筛查:乌干达卢姆萨巴的 CRAFFT 工具的翻译、改编和心理计量学评估。

Improving alcohol and substance use screening in school-age children: translation, adaptation and psychometric evaluation of the CRAFFT tool for Lumasaaba, Uganda.

机构信息

Department of Psychiatry, School of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.

Department of Psychiatry, Mulago National Referral and Teaching Hospital, Ministry of Health, Kampala, Uganda.

出版信息

Addict Sci Clin Pract. 2024 May 14;19(1):38. doi: 10.1186/s13722-024-00465-7.

Abstract

BACKGROUND

Children at risk of substance use disorders (SUD) should be detected using brief structured tools for early intervention. This study sought to translate and adapt the Car, Relax, Alone, Forget, Family/Friends, Trouble (CRAFFT) tool to determine its diagnostic accuracy, and the optimum cut-point to identify substance use disorders (SUD) risk in Ugandan children aged 6 to 13 years.

METHODS

This was a sequential mixed-methods study conducted in two phases. In the first qualitative phase, in Kampala and Mbale, the clinician-administered CRAFFT tool version 2.1 was translated into the local Lumasaaba dialect and culturally adapted through focus group discussions (FGDs) and in-depth interviews, in collaboration with the tool's authors. Expert reviews and translations by bilingual experts provided insights on linguistic comprehensibility and cultural appropriateness, while pilot testing with the target population evaluated the tool's preliminary effectiveness. In the second phase, the CRAFFT tool, adapted to Lumasaaba, was quantitatively validated against the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID) for diagnosing SUD in Mbale district, through a survey. Participants, chosen randomly from schools stratified according to ownership, location, and school size, were assessed for the tool's reliability and validity, including comparisons to the MINI KID as the Gold Standard for diagnosing SUD. Data were analyzed using STATA-15. Receiver-operating-characteristic analysis was performed to determine the sensitivity, specificity, and criterion validity of the CRAFFT with the MINI-KID.

RESULTS

Of the 470 children enrolled, 2.1% (n = 10) had missing data on key variables, leaving 460 for analysis. The median age and interquartile range (IQR) was 11 (9-12) years and 56.6% were girls. A total of 116 (25.2%) children had consumed alcohol in the last twelve-month period and 7 (1.5%) had used other substances. The mean CRAFFT score for all the children (n = 460) was 0.32 (SD 0.95). The prevalence of any alcohol use disorder (2 or more positive answers on the MINI KID) in the last 12 months was 7.2% (n = 32). The Lumasaaba version of the CRAFFT tool demonstrated good internal consistency (Cronbach's α = 0.86) and inter-item correlation (Spearman correlation coefficient of 0.84 (p < 0.001). At a cut-off score of 1.00, the CRAFFT had optimal sensitivity (91%) and specificity (92%) (Area Under the Curve (AUC) 0.91; 95% CI 0.86-0.97) to screen for SUD. A total of 62 (13.5%) had CRAFFT scores of > 1.

CONCLUSION

The Lumasaaba version of the CRAFFT tool has sufficient sensitivity and specificity to identify school-age children at risk of SUD.

摘要

背景

儿童期物质使用障碍(SUD)风险应通过简短的结构化工具进行检测,以便进行早期干预。本研究旨在翻译和改编 Car,Relax,Alone,Forget,Family/Friends,Trouble(CRAFFT)工具,以确定其诊断准确性和识别乌干达 6 至 13 岁儿童 SUD 风险的最佳切点。

方法

这是一项在两个阶段进行的顺序混合方法研究。在第一阶段的定性研究中,在坎帕拉和姆巴莱,临床医生管理的 CRAFFT 工具版本 2.1 被翻译成当地的卢马萨巴语方言,并通过焦点小组讨论(FGD)和深入访谈进行文化改编,与工具的作者合作。专家审查和双语专家的翻译提供了语言理解和文化适应性方面的见解,而目标人群的试点测试评估了工具的初步效果。在第二阶段,根据 Lumasaaba 改编的 CRAFFT 工具通过问卷调查在姆巴莱区定量验证了针对儿童和青少年的迷你国际神经精神病学访谈(MINI-KID)用于诊断 SUD。参与者从根据所有权、位置和学校规模分层的学校中随机选择,评估工具的可靠性和有效性,包括与 MINI KID 作为诊断 SUD 的金标准进行比较。使用 STATA-15 进行数据分析。进行接收者操作特征分析以确定 CRAFFT 与 MINI-KID 之间的敏感性、特异性和标准效度。

结果

在纳入的 470 名儿童中,有 2.1%(n=10)关键变量缺失数据,留下 460 名用于分析。中位数年龄和四分位间距(IQR)为 11(9-12)岁,56.6%为女孩。共有 116(25.2%)名儿童在过去 12 个月内饮酒,7(1.5%)名儿童使用过其他物质。所有儿童(n=460)的 CRAFFT 平均得分为 0.32(SD 0.95)。过去 12 个月任何酒精使用障碍(MINI KID 上有 2 个或更多阳性答案)的患病率为 7.2%(n=32)。卢马萨巴语版 CRAFFT 工具表现出良好的内部一致性(Cronbach's α=0.86)和条目间相关性(Spearman 相关系数为 0.84(p<0.001)。在 1.00 的截断分数下,CRAFFT 具有最佳的敏感性(91%)和特异性(92%)(曲线下面积(AUC)0.91;95%CI 0.86-0.97),可用于筛查 SUD。共有 62(13.5%)名儿童的 CRAFFT 评分>1。

结论

卢马萨巴语版 CRAFFT 工具具有足够的敏感性和特异性,可以识别有 SUD 风险的学龄儿童。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49f5/11095024/65fadb964df4/13722_2024_465_Fig1_HTML.jpg

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