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一名高血压未控制患者发生基底动脉血栓形成及延髓背外侧综合征。

Basilar artery thrombosis and Wallenberg syndrome in a patient with uncontrolled hypertension.

作者信息

Dakaj Nazim, Gocaj Kaltrina, Kabashi Serbeze, Dedushi Kreshnike, Blakaj Vullnet, Goçaj Alba

机构信息

Assistant Professor at Alma Mater Europea" Rezonanca", Specialist of Neurology, KSHM, Rezonanca, Veterrnik 10000, Prishtine, Kosove.

Radiology Resident in University Clincial Center of Kosova, Rrahim Beqiri, Pika Exclusive Llam B-41, Prishtine, Kosove.

出版信息

Radiol Case Rep. 2024 May 6;19(8):3033-3037. doi: 10.1016/j.radcr.2024.03.043. eCollection 2024 Aug.

DOI:10.1016/j.radcr.2024.03.043
PMID:38745978
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11091452/
Abstract

Presented here is a compelling case of a patient with a history of untreated hypertension, highlighting symptoms indicative of Wallenberg syndrome, including acute-onset dizziness, visual disturbances, continuous vomiting, difficulty walking, and an altered level of consciousness. This case's significance lies in its clinical presentation and in the diagnostic journey undertaken to elucidate its underlying pathology. Throughout the patient's hospitalization, a comprehensive assessment incorporating clinical, laboratory, and imaging techniques was conducted to delineate the extent of their condition. Of particular significance were the findings derived from MRI and MRA examinations of the endocranium, which provided crucial insights into the underlying pathophysiology. The MRI revealed multifocal ischemic lesions, pointing towards basilar artery thrombosis affecting both vertebral branches and displaying characteristic features associated with Wallenberg syndrome. Notably, the patient's lack of antihypertensive, anticoagulant, or antiplatelet therapy underscores the importance of addressing modifiable risk factors early in the disease course. This case serves as a poignant reminder of the complexities inherent in cerebrovascular diseases, highlighting the imperative of prompt recognition and management of predisposing factors. By presenting this case, we aim to underscore the clinical significance of timely intervention in mitigating potential complications of hypertension, such as cerebral artery thrombosis, thereby emphasizing the importance of proactive patient care and risk factor modification in clinical practice.

摘要

本文介绍了一例令人关注的病例,患者有未治疗的高血压病史,突出了提示延髓背外侧综合征的症状,包括急性发作的头晕、视觉障碍、持续呕吐、行走困难和意识水平改变。该病例的意义在于其临床表现以及为阐明其潜在病理所进行的诊断过程。在患者住院期间,进行了综合评估,包括临床、实验室和影像学检查,以明确其病情程度。颅内MRI和MRA检查的结果尤为重要,为潜在的病理生理学提供了关键见解。MRI显示多灶性缺血性病变,提示基底动脉血栓形成累及双侧椎动脉分支,并表现出与延髓背外侧综合征相关的特征。值得注意的是,患者未接受抗高血压、抗凝或抗血小板治疗,这凸显了在疾病病程早期应对可改变的危险因素的重要性。该病例深刻提醒人们脑血管疾病固有的复杂性,突出了及时识别和处理诱发因素的紧迫性。通过展示这个病例,我们旨在强调及时干预以减轻高血压潜在并发症(如脑动脉血栓形成)的临床意义,从而强调在临床实践中积极的患者护理和危险因素调整的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56e2/11091452/50d0b4880524/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56e2/11091452/37871205cd05/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56e2/11091452/db765df1509b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56e2/11091452/3e811df538d4/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56e2/11091452/50d0b4880524/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56e2/11091452/37871205cd05/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56e2/11091452/db765df1509b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56e2/11091452/3e811df538d4/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56e2/11091452/50d0b4880524/gr4.jpg

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本文引用的文献

1
Lateral medullary syndrome: uncommon form of brainstem stroke.延髓外侧综合征:一种罕见的脑干卒中形式。
Ann Med Surg (Lond). 2023 Feb 17;85(3):542-544. doi: 10.1097/MS9.0000000000000260. eCollection 2023 Mar.
2
The Modifiable Risk Factors of Uncontrolled Hypertension in Stroke: A Systematic Review and Meta-Analysis.中风中未控制高血压的可改变危险因素:一项系统评价与荟萃分析
Stroke Res Treat. 2021 Feb 24;2021:6683256. doi: 10.1155/2021/6683256. eCollection 2021.
3
Clinical Importance of the Posterior Inferior Cerebellar Artery: A Review of the Literature.
后下小脑动脉的临床重要性:文献回顾。
Int J Med Sci. 2020 Oct 18;17(18):3005-3019. doi: 10.7150/ijms.49137. eCollection 2020.
4
Neuroanatomical basis of Wallenberg syndrome.延髓背外侧综合征的神经解剖学基础。
Cir Cir. 2020;88(3):376-382. doi: 10.24875/CIRU.19000801.
5
Public Awareness of Health-Related Risks From Uncontrolled Hypertension.公众对未控制的高血压相关健康风险的认识。
Prev Chronic Dis. 2018 Apr 5;15:E40. doi: 10.5888/pcd15.170362.
6
Basilar artery occlusion.基底动脉闭塞。
Lancet Neurol. 2011 Nov;10(11):1002-14. doi: 10.1016/S1474-4422(11)70229-0.