Department of Chemistry, Faculty of Science, Dicle University, Diyarbakir, Turkiye.
Tokat Gaziosmanpasa University, Faculty of Science and Arts, Chemistry Department, 60250 Tokat, Turkiye; Dr M. A. Kazi Institute of Chemistry, University of Sindh, Jamshoro, Sindh, Pakistan.
Food Chem. 2024 Sep 30;453:139632. doi: 10.1016/j.foodchem.2024.139632. Epub 2024 May 15.
A new magnetic nano gel (MNG) was prepared from choline chloride/phenol deep eutectic solvent and magnetic amberlite XAD-7 nanocomposite. The dispersive solid phase micro extraction (dSPME) method was developed for seperation and preconcentration of Brilliant Blue FCF (BB) by the prepared MNG. In this study, firstly, the optimum DES type and mole ratio of DES were investigated before response surface methodology optimization. Then, the effect of the MNG-dSPME experimental parameters were optimized by response surface methodology using central composite design. Under the optimum microextraction conditions, limit of detection (LOD), limit of quantification (LOQ), preconcentration factor (PF), enhencament factor (EF) were found to be 1.15 μg L,3.80 µg L, 70, and 88, respectively. It was seen that the recovery of real samples were obtained from 95.5 to 103.6%. The pesent method was succesfully for extraction of BB in some food, personal care samples, to the best of our knowledge, this is the first study that is presented method on determination of BB by preconcentration with magnetic nano gel. The obtained results showed that the present procedure is effective, sensitive, and has high accuracy for the quantitative detection of BB.
一种新型的磁性纳米凝胶（MNG）由氯化胆碱/苯酚深共晶溶剂和磁性 Amberlite XAD-7 纳米复合材料制备而成。采用制备的 MNG 发展了用于分离和预浓缩亮蓝 FCF（BB）的分散固相微萃取（dSPME）方法。在本研究中，首先在响应面方法优化之前研究了最佳 DES 类型和 DES 的摩尔比。然后，通过中心复合设计的响应面法优化了 MNG-dSPME 实验参数。在最佳微萃取条件下，检测限（LOD）、定量限（LOQ）、预浓缩因子（PF）和增强因子（EF）分别为 1.15μg L、3.80μg L、70 和 88。从 95.5%到 103.6%的实际样品回收率。本方法成功地用于一些食品、个人护理样品中 BB 的提取，据我们所知，这是首次提出的通过磁性纳米凝胶预浓缩测定 BB 的方法。所得结果表明，本方法对于 BB 的定量检测是有效、灵敏且具有高准确度的。
