Meeker H C, Eskew M L, Scheuchenzuber W, Scholz R W, Zarkower A
J Leukoc Biol. 1985 Oct;38(4):451-8. doi: 10.1002/jlb.38.4.451.
Experiments were performed to determine the effects of dietary selenium and/or vitamin E deficiency on cell-mediated cytotoxicity in the mouse. Natural killer cell-mediated cytotoxicity (NKCC) was depressed after 8 wk on diets deficient in selenium and/or vitamin E. In contrast, antibody-dependent cell-mediated cytotoxicity (ADCC) was not affected by 8 wk of dietary deficiency of selenium and/or vitamin E. T-lymphocyte-mediated cytotoxicity (TCMC) was found to be depressed by combined selenium-vitamin E deficiency after 7 weeks on diets.
进行实验以确定膳食中硒和/或维生素E缺乏对小鼠细胞介导的细胞毒性的影响。在食用缺乏硒和/或维生素E的饮食8周后，自然杀伤细胞介导的细胞毒性（NKCC）降低。相比之下，抗体依赖性细胞介导的细胞毒性（ADCC）不受8周膳食中硒和/或维生素E缺乏的影响。在食用缺乏硒和维生素E的饮食7周后，发现T淋巴细胞介导的细胞毒性（TCMC）降低。
