Department of Diagnostic Radiology, Nagano Red Cross Hospital, 5-22-1 Wakasato, Nagano, 380-8582, Japan.
Radiol Phys Technol. 2024 Sep;17(3):651-657. doi: 10.1007/s12194-024-00814-w. Epub 2024 May 17.
This study aimed to determine the scan delay for bolus tracking in the hepatic artery phase (HAP) of hepatic dynamic computed tomography (CT) using the cardiothoracic ratio (CTR) from CT scout images. We retrospectively studied 188 patients who underwent hepatic dynamic CT, 24 of whom had scan delays adjusted for CTR. The contrast enhancement of the abdominal aorta, portal vein, hepatic vein, and hepatic parenchyma was calculated for HAP. The adequacy of the scan timing for HAP was assessed using three classifications: early, appropriate, or late. The effect of HAP on scan timing adequacy was determined using multivariate logistic regression analysis, and the optimal cutoff value of CTR was evaluated using receiver operating characteristic analysis. The trigger times for bolus tracking (odds ratio: 1.58) and CTR (odds ratio: 1.23) were significantly affected by the appropriate scan timing of the HAP. The optimal cutoff value of CTR was 59.3%. The scan timing of HAP with a scan delay of 15 s was 14% of early and 86% of appropriate, and the proportion of early in CTR ≥ 60% (early, 52%; appropriate, 48%) was higher than that in CTR < 60% (early, 6%; appropriate, 94%). Adjusting the scan delay to 20 s in CTR ≥ 60% increased the proportion of appropriate (early, 4%; appropriate, 96%). The CTR of a CT scout image is an effective index for determining the scan delay for bolus tracking. Adjusting the scan delay by CTR can provide appropriate HAP images in more patients. Trial registration number: R-080; date of registration: 9 March 2023, retrospectively registered.
本研究旨在通过 CT 扫描的心胸比(CTR)来确定肝脏动态 CT(CT)肝动脉期(HAP)中团注追踪的扫描延迟时间。我们回顾性研究了 188 例接受肝脏动态 CT 检查的患者,其中 24 例根据 CTR 调整了扫描延迟时间。计算了 HAP 时腹主动脉、门静脉、肝静脉和肝实质的对比增强情况。使用三种分类法评估 HAP 的扫描时间是否合适:过早、合适或过晚。使用多元逻辑回归分析确定 HAP 对扫描时间合适性的影响,使用受试者工作特征分析评估 CTR 的最佳截断值。追踪团注的触发时间(优势比:1.58)和 CTR(优势比:1.23)均受到 HAP 合适扫描时间的显著影响。最佳 CTR 截断值为 59.3%。CTR 为 59.3%时 HAP 的扫描延迟时间为 15 秒,过早的比例为 14%,合适的比例为 86%,而 CTR≥60%时(过早:52%;合适:48%)早期比例高于 CTR<60%(过早:6%;合适:94%)。在 CTR≥60%时将扫描延迟时间调整为 20 秒可增加合适的比例(过早:4%;合适:96%)。CT 扫描的 CTR 是确定团注追踪扫描延迟时间的有效指标。通过 CTR 调整扫描延迟时间可以为更多患者提供合适的 HAP 图像。试验注册号:R-080;注册日期:2023 年 3 月 9 日,回顾性注册。